Results 91 to 100 of about 486,020 (305)

Deep sedation in patients undergoing atrioventricular nodal reentry tachycardia ablation

Research in Cardiovascular Medicine, 2013
Background: General anesthesia and deep sedation can be used during cardiac EPS to relief pain and provide comfort and immobility, but many electrophysiologists avoid sedation for better arrhythmia induction. Objective: To determine anesthesia effects in
Amirfarjam Fazelifar, Ali Eskandari, Mohammadjafar Hashemi, Mostafa Alavi, Mohammadzia Totounchi, Azam Forghanian, Mahboubeh Zeighami, Zahra Emkanjoo, Majid Haghjoo   +8 more
doaj   +1 more source

Use of total intravenous anesthesia dexmetomidine

, 2011
La dexmedetomidina Inicialmente se uso en unidades de cuidados intensivos para sedación. Sin embargo, sus efectos sedantes, analgésicos y ansiolíticos sin alteración de la función ventilatoria, permiten ampliar su uso en cirugía como anestésico ...
García Botero, Andrés
core  

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Effects of balanced anesthesia with sevoflurane-remifentanil and total intravenous anesthesia with propofol-remifentanil on postoperative stress responses in patients with stomach cancer [PDF]

, 2014
Background:The effects of anesthetics on postoperative stress response remains not fully understood. We evaluated the effects of sevoflurane-remifentanil balanced anesthesia and propofol- remifentanil total intravenous anesthesia (TIVA) on postoperative ...
김혜진, 남상범, 이수현, 이종석   +3 more
core  

Does a combined intravenous-volatile anesthesia offer advantages compared to an intravenous or volatile anesthesia alone

, 2021
\(\bf Background\) In anesthesia, additive drug interactions are used for reducing dose and dose-dependent side-effects. The combination of propofol with volatile anesthetics is rather unusual but might have advantages compared to the single use ...
Selpien, Helene (Dr. med.), Haberl, Helge, Unterberg, Matthias (Dr. med.), Wolf, Alexander (Dr. med.)   +3 more
core  

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

Advanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song, Melissa Cadena, Myeongsoo Kim, Euisuk Chung, Jeungyoon Lee, Zlata Brushevich, Seonghun Shin, Paul S. Pelkowski, Stanislav Y. Emelianov   +8 more
wiley   +1 more source

Application of propofol-remifentanil intravenous general anesthesia combined with regional block in pediatric ophthalmic surgery

BMC Anesthesiology
Objective The aim of this study is to observe the anesthetic effect and safety of intravenous anesthesia without muscle relaxant with propofol-remifentanil combined with regional block under laryngeal mask airway in pediatric ophthalmologic surgery ...
Ming-Ying Li, Yu-Da Fei, Xiao-Xia Zhang, Tian-Wen Chen, Jie Li, Xiao-Li Sun, Zhen-Yuan Wang   +6 more
doaj   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Comparison of correlation dimension and fractal dimension in estimating level of consciousness

, 2009
This paper compares the correlation dimension (D2) ,Higuchi fractal dimension (HFD),Katz fractal dimension(KFD)and Sevcik fractal dimension(SFD) approaches in estimating Depth of Anesthesia (DOA) based on of electroencephalogram (EEG). The single-channel
Zaghari, Bahareh
core   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source