Results 131 to 140 of about 150,871 (308)

Adding Dexmedetomidine to Lidocaine for Intravenous Regional Anesthesia

, 2004
Dexmedetomidine is approximately 8 times more selective toward the ?-2-adrenoceptors than clonidine. It decreases anesthetic requirements by up to 90% and induces analgesia in patients.
Turan A., Memiş D., Karamanlio?lu B., Pamukçu Z., Kurt I.   +4 more
core   +1 more source

Estudo comparativo do propofol com o midazolam para a sedação, a curto prazo, de pacientes sob ventilação mecanica internada em UTI [PDF]

, 1998
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias da SaudeFoi realizado um estudo clínico aberto, controlado e randomizado em 30 pacientes adultos, com o objetivo de comparar a segurança e a eficácia do propofol a do ...
Moritz, Rachel Duarte
core  

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Intravenous anesthetics during the induction and maintenance of anesthesia.

Intravenous anesthetics during the induction and maintenance of anesthesia.
Xiaowen Ma (845262), Diansan Su (298369), Ying Tang (231843), Yuwen Chen (7055768), Ming Zhang (9736), Dawei Li (5704), Ziyu Zhu (6682841), Xiaoying Chi (11893556)   +7 more
core   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

Clinical Experience of Total Intravenous Anesthesia in 77 Renal Transplant Patients

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Purpose:Renal transplantation significantly improves quality of life compared to hemodialysis in patients with end-stage renal failure. In end-stage renal failure anesthetic technique should be planned carefully, due to changes in volume distribution ...
Pinar Ergenoglu, Cagla Bali, Sule Akin, Nesrin Bozdogan Ozyilkan, Hacer Ulger, Anis Aribogan   +5 more
doaj  

Research of sedation for dentistry : Part 3. Method of additional injection for Midazolam intravenous sedation during operation

, 2000
P(論文)We have actively used intravenous sedation with monitored conscious sedation care for cases of dental and minor oral surgical procedures under local anesthesia.
大桶,華子, 26041, 加藤,元康, OHKE,Hanako/KUDO,Masaru/KATO,Motoyasu/KAWAI,Takurou/SATO,Yuki/KATAGIRI,Kazuhito/KOKUBU,Masahiro/SHINYA,Noboru, 新家,昇, 工藤,勝, 河合,拓郎, 片桐,和人, 26039, 國分,正廣, 佐藤,雄季   +10 more
core  

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source