Objective The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) in glucocorticoid (GC)‐dependent polymyalgia rheumatica (PMR). TCZ reduced GC use and disease activity at 24 weeks. This study aimed to assess relapse rates after stopping TCZ in patients achieving remission at week 24.
Baptiste Chevet+24 more
wiley +1 more source
Effects of different doses of remifentanil combined with sevoflurane anesthesia on postoperative analgesia and hemodynamics in pediatric patients undergoing laparoscopic inguinal hernia repair. [PDF]
Ma J, Wang Y, Liu Z, Han S.
europepmc +1 more source
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens+14 more
wiley +1 more source
Multimodal anesthesia for hemicorporectomy suggests creating a standardized anesthesia guideline: a case report. [PDF]
Repine KM+3 more
europepmc +1 more source
Clinical Images: Acute vision loss due to granulomatosis with polyangiitis
Arthritis &Rheumatology, EarlyView.
Hirotaka Yamamoto, Yoshinori Taniguchi
wiley +1 more source
Inappropriate and overuse of antimicrobials is increasing antimicrobial resistance. Understanding physicians' antimicrobial decision‐making is essential for developing interventions to optimize prescribing. The aim of this review was to identify the factors that influence physicians' antimicrobial prescribing decisions.
Savannah Reali+4 more
wiley +1 more source
Extended Postoperative Analgesia via Caudal Catheters for Major Surgery in Neonates-A 6-Year Retrospective Study. [PDF]
Heschl S+4 more
europepmc +1 more source
Abstract Aims Antimicrobial prophylaxis is central in preventing postoperative spine infections, yet knowledge on clinical target spine tissue concentrations remain limited. Current dosing regimens often involve fixed doses based on empirical knowledge, surrogate measures, non‐clinical evidence and methodology of variying quality.
Magnus Andreas Hvistendahl+6 more
wiley +1 more source
Balanced Opioid-Free Anesthesia on Chronic Postsurgical Pain After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial Protocol. [PDF]
Huo WW+6 more
europepmc +1 more source
The Median Effective Concentration (EC50) of Alfentanil Combined with Propofol Closed-Loop Targeted Infusion in Super-Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP). [PDF]
Sun Z, Li W, Zhong Y, Lang B, Luo Y.
europepmc +1 more source