Results 61 to 70 of about 486,020 (305)

Local versus general anesthesia for transcatheter aortic valve implantation (TAVR)- systematic review and meta-analysis [PDF]

, 2014
The hypothesis of this study was that local anesthesia with monitored anesthesia care (MAC) is not harmful in comparison to general anesthesia (GA) for patients undergoing Transcatheter Aortic Valve Implantation (TAVR).TAVR is a rapidly spreading ...
Webb, J, Reinthaler, M, Georg M Fröhlich, Marco Roffi, Olaf Wendler, Nevil Hutchinson, Markus Reinthaler, Duolao Wang, David Hildick-Smith, Wang, D, Hutchinson, N, Fröhlich, GM, John Webb, Pascal Meier, Alexandra J Lansky, Wendler, O, Hildick-Smith, D, Stefan Toggweiler, Lansky, AJ, Roffi, M, Meier, P, Toggweiler, S   +21 more
core   +2 more sources

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Electroencephalogram fractal dimension as a measure of depth of anesthesia

, 2008
This paper proposes a combined method including adaptive segmentation and Higuchi fractal dimension (HFD) of electroencephalograms (EEG) to monitor depth of anesthesia (DOA).
Zaghari, Bahareh, Negahbani, Ehsan, Amirfattahi, Rasool, Rouzbeh, Mohmmad, Dehnavi, Alireza Mehri, Ahmadi, Behzad, Hashemi, Zeinab   +6 more
core   +1 more source

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Effect of intravenous dexamethasone in dimishing alfentanyl-induced-cough [PDF]

Background & objectives: The use of synthetic opioids (fentanil, alfentanil, …) has been increasing as they can induce anesthesia without histamine release to the stress caused by anesthesia and can cause an effective analgesia at first cut.
نوروزی, ودود, محمدیان اردی, علی   +1 more
core  

Department of Anesthesia. University of Iowa. Spring 2009. [PDF]

, 2009
University of Iowa Department of Anesthesia ...

core  

Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]

, 2010
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Raewer, Helen-Caroline, Helen-Caroline Räwer, Wolfgang Sieber, Sieber, Wolfgang, Walker, Annett Isabel, Annett Isabel Walker, Przybilla, Bernhard, Bernhard Przybilla   +7 more
core   +1 more source