Results 231 to 240 of about 431,288 (313)

Ultrasound-guided intermediate cervical plexus block versus local infiltration anesthesia for thermal ablation of benign thyroid nodules: a non-inferior, double-blinded, randomized controlled trial. [PDF]

BMC Anesthesiol
Huang P, Zhu K, Wu T, Zheng B, Yin T, Wang N, Lian Y, He Y, Li Y, Yang J, Ren J, Zhang Z.   +11 more
europepmc   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

Trifecta outcomes to assess the feasibility of local anesthesia for benign prostate hyperplasia minimally invasive surgical treatments. [PDF]

Urol Ann
Olivero A, Khadhouri S, Palagonia E, Dell'Oglio P, Tappero S, Dreyer B, Bocciardi AM, Caviglia A, Galfano A, Al Jaafari F, Somani BK, Pietropaolo A, Secco S.   +12 more
europepmc   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Comparative Evaluation of the Effectiveness of 2% Lignocaine Mixed With Dexamethasone 4 mg vs. 2% Lignocaine (1:200,000 Epinephrine) for Pain Control During the Removal of Orthodontically Indicated Mandibular Premolars: A Randomized Controlled Trial. [PDF]

Cureus
Malikar HK, Bang K, Shenoi R, Kolte V, Agrawal N, Dahake R, Jadhav KD, Oommen T.   +7 more
europepmc   +1 more source

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

Spinal anesthesia with caudal catheter in pediatric urologic surgery: an alternative to general anesthesia. [PDF]

Front Pediatr
Stangl-Kremser J, Puttmann K, Alpert SA, Ching C, DaJusta D, Fuchs M, McLeod D, Jayanthi VR, Ebert K.   +8 more
europepmc   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Erector Spinae Plane Block With Liposomal Bupivacaine for Cervical Spine Surgery. [PDF]

Case Rep Anesthesiol
Peterson H, Nassr A, Kerfeld M.
europepmc   +1 more source