Results 231 to 240 of about 5,124,662 (283)

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang   +9 more
wiley   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu   +9 more
wiley   +1 more source

Local anesthesia is associated with better functional outcomes than conscious sedation in endovascular thrombectomy for acute ischemic stroke: A retrospective analysis of the OPTIMISE registry.

open access: yesInterv Neuroradiol
Mendes GN   +11 more
europepmc   +1 more source

Efficacy and Safety of Different Local Anesthesia Techniques in Podiatric Procedures. [PDF]

open access: yesMedicina (Kaunas)
Trevissón Redondo B   +8 more
europepmc   +1 more source

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