Results 251 to 260 of about 1,034,377 (353)

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Exploratory Laparotomy With Enhanced Recovery Under Combined Thoracic Segmental Spinal and Epidural Anesthesia in a High-Risk Elderly Patient: A Case Report. [PDF]

Cureus
Ravindran A, Khan IA, Shetty S.
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Potential Effects of Three Forms of Sialic Acid on Intestinal Health in Obese Mice Fed With a High‐Fat Diet

Food Frontiers, EarlyView.
A high‐fat diet impairs intestinal health by disrupting the mucus layer, widening epithelial gaps, triggering inflammation, and causing microbial dysbiosis, ultimately leading to obesity and metabolic disorders. Sialic acid interventionsparticularly bound forms (3ʹ‐SL and EBN)outperform free Neu5Ac in restoring microbial balance, alleviating ...
Xinyue Wang, Wei Zhang, Xinyuan Huang, Linlin Zhou, Xinning Zhao, Hanying Zheng, Xudan Shen, Xinyi Wang, Lili Pan, Yahui Li, Hongwei Li   +10 more
wiley   +1 more source

Effect of Prophylactic Phenylephrine Infusion Versus Interventional Ephedrine Boluses on Umbilical Blood pH in Cesarean Deliveries Under Spinal Anesthesia: A Retrospective Case-Control Study. [PDF]

J Clin Med
Horosz B, Białowolska-Horosz K, Malec-Milewska M.   +2 more
europepmc   +1 more source

Nobiletin Ameliorates Aβ1–42‐Induced Cognitive Disorder and Mitochondrial Dysfunction via Targeting the Key Circadian Regulator Bmal1

Food Safety and Health, EarlyView.
Nobiletin (NOB) ameliorates Aβ‐induced Alzheimer’s pathology by restoring circadian rhythm via Bmal1. NOB rescues cognitive deficits, synaptic damage, and mitochondrial dysfunction in mice and neurons by enhancing Bmal1/Clock oscillations and downstream mitochondrial integrity, positioning circadian regulation as a therapeutic target for Alzheimer's ...
Huajing Gao, Qinglin Qu, Ning Wang, Xue Gao, Peihua Li, Yanquan Mou, Xiangrui Kong, Yannan Chen, Dapeng Li, Xintong Tan   +9 more
wiley   +1 more source

Is Spinal Analgesia or Anesthesia Safe After Labor Epidural Analgesia? Reporting Two Cases of High Neuraxial Block and Mini-Review of the Literature. [PDF]

Reports (MDPI)
Uvelin A, Cavrić-Dragičević M, Pujić B, Jovanović L, Tubić T, Popović R.   +5 more
europepmc   +1 more source

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

Glia, EarlyView.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz, José L. Dena‐Beltrán, Marco A. Dimas‐Rufino, Ximena Castillo, Dina I. Vazquez‐Carrillo, Andrea Silos‐Guajardo, Xarubet Ruiz‐Herrera, Edith Garay, Gonzalo Martínez de la Escalera, Carmen Clapp, Rogelio O. Arellano, Abraham J. Cisneros‐Mejorado, Yazmín Macotela   +12 more
wiley   +1 more source

Effects of spinal versus general anesthesia on serum oxidative stress markers and cytokine release after abdominal hysterectomy: a non-randomized trial. [PDF]

Sci Rep
Hashemian M, Sahebdad-Khabisi S, Honarvar Z, Torabinejad Z, Taravati H, Mohammadi FD, Amirkhosravi L.   +6 more
europepmc   +1 more source