Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source
Efficacy and safety of remimazolam for induction and maintenance of general anesthesia in day surgery: a randomized controlled non-inferiority clinical trial. [PDF]
Liang KY+5 more
europepmc +1 more source
A NEW, SIMPLE AND PRACTICAL NEEDLE FOR INTRAVENOUS ANESTHESIA [PDF]
Torsten Gordh
openalex +1 more source
A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring
This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee+9 more
wiley +1 more source
General anesthesia with spontaneous breathing and laryngeal mask airway intubation combined with peripheral nerve block in orthopedic surgery: a retrospective study. [PDF]
Tu J, Peng P, Xiong Z.
europepmc +1 more source
ABDUCENS NERVE PALSY FOLLOWING SPINAL ANESTHESIA [PDF]
CAPTAIN BENJAMIN STEINBERG+1 more
openalex +1 more source
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras+19 more
wiley +1 more source
The impact of spontaneous ventilation anesthesia on thrombosis risk for thoracic surgery: a beagle dog model study. [PDF]
Zeng Y+7 more
europepmc +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao+5 more
wiley +1 more source