The Impact of Electroencephalogram-Guided General Anesthesia on Postoperative Delirium and Recovery in Patients Over 60 with Hip Fractures: A Retrospective Cohort Study. [PDF]
Neuropsychiatr Dis TreatLiu Y, Fan H, Wei G, Shu Y, Zhang J.
europepmc +1 more source
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Erector spinae plane block for pain management in lumbar percutaneous vertebroplasty: study protocol for a randomized controlled trial. [PDF]
PeerJLi A, Zhao Y, Li Y, Wang X.
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Advanced Functional Materials, EarlyView.This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
Serum HMGB1 levels in elderly patients undergoing general anesthesia with dexmedetomidine and its correlation with early postoperative cognitive dysfunction. [PDF]
Medicine (Baltimore)Zhou H +5 more
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Advanced Functional Materials, EarlyView.A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz +7 more
wiley +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Study on the effective dose of alfentanil combined with ciprofol in inhibiting intraoperative body movement responses in patients undergoing breast lump resection. [PDF]
Front Med (Lausanne)Li F, Lu Y, Lu G, Gu J, Zhu Y.
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Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions
Advanced Functional Materials, EarlyView.An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park +10 more
wiley +1 more source
Anesthetic Management of a Pregnant Woman With an Unruptured Cerebral Aneurysm Undergoing Simultaneous Cesarean Section and Craniotomy for Aneurysm Clipping: A Case Report. [PDF]
Case Rep AnesthesiolOkubo K +4 more
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