Results 301 to 310 of about 1,478,510 (392)

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Impact of anesthesia type on postoperative pain and outcomes in primary hip and knee arthroplasty: a retrospective register analysis. [PDF]

BMC Anesthesiol
Sponheuer K, Becker-Rux D, Scheike S, Barsch L, Pempe C, Pfrepper C, Roth A, Werdehausen R.   +7 more
europepmc   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Nerve block or fascial block: This is the question. [PDF]

Saudi J Anaesth
Fusco P, Petroni GM, De Sanctis F, Maggiani C, Nazzarro E.   +4 more
europepmc   +1 more source

Comparison of Two Newer Anesthetic Drugs Used in Obtaining Lumbar Epidural Anesthesia.

, 1954
F. Paul Ansbro, Albert E. Blundell, Joseph C. Sweeney, Benson Bodell, Julius E. Andorko   +4 more
openalex   +1 more source

Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers

Advanced Healthcare Materials, EarlyView.
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao, Zheng Zhang, Xincai Wu, Yanwei Chen, Wenjun Li, Jiayan Bao, Xin Zhang, Baoding Chen   +7 more
wiley   +1 more source

Effective anesthesia management for super obesity-related compartment syndrome with ultrasound and Doppler guidance: A different strategy. [PDF]

Saudi J Anaesth
Gentili L, Guerriero G, Nania F, Angeletti C.   +3 more
europepmc   +1 more source

Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation

Advanced Healthcare Materials, EarlyView.
MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng, Li‐Ling Chen, Guan‐Jhong Tseng, Jun‐Xuan Huang, Yen‐Jing Ting, Po‐Han Chiang   +5 more
wiley   +1 more source

Navigating Complexity: Anesthesia for Hip Fracture Surgery in an Elderly Patient With Multiple Comorbidities. [PDF]

Cureus
Khalaf AA, Abuamra KS, Ibrahim H, Nabil A.   +3 more
europepmc   +1 more source

Evaluation of Changing Concepts in General Anesthesia as They Apply to Office Administration for Oral Surgery.*

, 1951
Maurice J. Oringer
openalex   +1 more source