Results 101 to 110 of about 396,384 (358)

Palliative Care Principles and Anesthesiology Clinical Practice: Current Perspectives

open access: gold, 2021
Giulia Catalisano   +4 more
openalex   +2 more sources

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang   +18 more
wiley   +1 more source

Trends and Emerging Research Areas in Postoperative Sleep Disturbances: A Bibliometric Analysis

open access: yesNature and Science of Sleep
Wei Du, Xi Qiao, Wei Liu, Chao Li, Huiqun Jia Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, People’s Republic of ChinaCorrespondence: Huiqun Jia, The Fourth Hospital of Hebei Medical ...
Du W, Qiao X, Liu W, Li C, Jia H
doaj  

Neuroinflammation is a putative target for the prevention and treatment of perioperative neurocognitive disorders. [PDF]

open access: yes, 2019
IntroductionThe demographics of aging of the surgical population has increased the risk for perioperative neurocognitive disorders in which trauma-induced neuroinflammation plays a pivotal role.Sources of dataAfter determining the scope of the review ...
Lai, IK, Li, R, Maze, M, Saxena, S
core   +2 more sources

The Abbreviated Maslach Burnout Inventory Can Overestimate Burnout: A Study of Anesthesiology Residents

open access: yesJournal of Clinical Medicine, 2019
The Maslach Burnout Inventory for healthcare professionals (MBI-HSS) and its abbreviated version (aMBI), are the most common tools to detect burnout in clinicians.
W. Lim   +6 more
semanticscholar   +1 more source

All‐Hydrogel‐Based Organic Electrochemical Transistors for Implantable Physiological Signal Monitoring

open access: yesAdvanced Science, EarlyView.
All‐hydrogel based n‐type depletion‐mode OECTs is developed using a semiconductor hydrogel formed via ionic‐liquid‐mediated phase separation, combining efficient ion‐electron transport, tissue‐like softness, and long‐term biocompatibility. The device can monitor EOG and ECG on human skin and record real‐time ECG subcutaneously in rats, providing a ...
Qicheng Liang   +14 more
wiley   +1 more source

The Optimal Patient Profile and Appropriate Role of Spinal Cord Stimulation (SCS) for Patients with Persistent Spinal Pain Syndrome-Type 1 (PSPS-T1) Not Suitable for Spine Surgery: A European Modified Delphi Consensus

open access: yesJournal of Pain Research
Tobias L Schulte,1 María Reyes Fernández-Marín,2 Roberto Gazzeri,3 Oliver Hamel,4 Jan Willem Kallewaard,5,6 Kavita Poply,7,8 Iris Smet,9 Jan Vesper,10 Erik Van de Kelft11,12 1Department of Orthopedics and Trauma Surgery, Katholisches Klinikum Bochum - St.
Schulte TL   +8 more
doaj  

Anesthesia for Minimally Invasive Coronary Artery Bypass Surgery

open access: yesJournal of Cardiovascular Development and Disease
Minimally invasive coronary artery bypass grafting (MI-CABG) has emerged as a transformative approach to coronary revascularization, offering reduced morbidity, faster recovery and improved cosmesis compared to conventional coronary artery bypass ...
Miranda Holmes   +3 more
doaj   +1 more source

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