Results 51 to 60 of about 300,051 (368)

Study protocol for the Anesthesiology Control Tower—Feedback Alerts to Supplement Treatments (ACTFAST-3) trial: A pilot randomized controlled trial in intraoperative telemedicine [version 1; referees: 2 approved] [PDF]

, 2018
Background: Each year, over 300 million people undergo surgical procedures worldwide. Despite efforts to improve outcomes, postoperative morbidity and mortality are common.
ACTFAST Study Group,, Avidan, Michael S, Ben Abdallah, Arbi, Fritz, Bradley A, Gregory, Stephen, Helsten, Daniel L, Murray-Torres, Teresa M, Sharma, Anshuman, Wildes, Troy S   +8 more
core   +2 more sources

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

Advanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li, Yehui Wu, Yihan Wang, Yumin Wu, Rong Hu, Si Long, Wenqi Huang, Liming Nie, Zhongxing Wang   +8 more
wiley   +1 more source

Decoding the Molecular Universe -- Workshop Report [PDF]

arXiv, 2023
On August 9-10, 2023, a workshop was convened at the Pacific Northwest National Laboratory (PNNL) in Richland, WA that brought together a group of internationally recognized experts in metabolomics, natural products discovery, chemical ecology, chemical and biological threat assessment, cheminformatics, computational chemistry, cloud computing ...
arxiv  

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L, Krafft, Paul R, Leitzke, Arthur S, Tang, Jiping, Van Allen, Nicole R, Zhang, John H   +5 more
core   +1 more source

Driving pressure during general anesthesia for open abdominal surgery (DESIGNATION) : study protocol of a randomized clinical trial [PDF]

, 2020
Background Intraoperative driving pressure (Delta P) is associated with development of postoperative pulmonary complications (PPC). When tidal volume (V-T) is kept constant, Delta P may change according to positive end-expiratory pressure (PEEP)-induced
Aarts, Leon P. H. J., Akkerman, Ronald D. L., Albersen, Juliette J. E., Aurilio, Caterina, Battaglini, Denise, Boer, Christa, Boom, Annemieke, Brouwer, Tammo, Buhre, Wolfgang F. F. A., Bulte, Carolina S. E., de Abreu, Marcelo Gama, de Boer, Hans D., De Korte-de Boer, Dianne J., Edward-Rutten, Gitara M., Godfried, Marc B., Helmerhorst, Hendrik J. F., Hemmes, Sabrine N. T., Hofland, Jan, Hol, Liselotte, Hol, Liselotte, Hollmann, Markus W., Hoogenboom, Hester, Houweling, Bernard M., Huhn, Ragnar, In 't Veld, Bastiaan A., Konijn, Wanda, Koopman-van Gemert, Ankie W. M. M., Kortekaas, Minke C., Neto, Ary Serpa, Nijbroek, Sunny G. L. H., Pelosi, Paolo, Preckel, Benedikt, Rad, Mandana, Sansone, Pasquale, Schultz, Marcus J., Stamkot, Andre, Stolker, Robert Jan, Struys, Michel, Ten Hoope, W., Thiel, Bram, Ubben, Johannes F. H., van der Zwan, Tim, Van Lier, Felix, Wrigge, Hermann, Zeillemaker-Hoekstra, Miriam, Zwijsen, Johannes H. M. J.   +45 more
core   +2 more sources

Caspase‐6/Gasdermin C‐Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2‐Dependent Recruitment of Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
Hypoxic and low‐glucose conditions in tumor tissues trigger colorectal tumor cell pyroptosis via sequential activation of the Caspase‐1/Caspase‐6/GSDMC axis. High mobility group box 1 (HMGB1), released from GSDMC‐mediated pyroptotic tumor cells, upregulates CXCL2 expression in adjacent tumor cells, thereby recruiting myeloid‐derived suppressor cells ...
Hanchao Gao, Yikun Yao, Weilong Li, Zigan Xu, Wenjun Hu, Kewang Luo, Peishan Chen, Wanjing Shang, Shaodong Luan, Guojun Shi, Mengtao Cao, Pengfei Chen   +11 more
wiley   +1 more source

Development of an Objective Structured Clinical Examination as a Component of Assessment for Initial Board Certification in Anesthesiology. [PDF]

, 2020
With its first administration of an Objective Structured Clinical Examination (OSCE) in 2018, the American Board of Anesthesiology (ABA) became the first US medical specialty certifying board to incorporate this type of assessment into its high-stakes ...
Cole, Daniel J, Dainer, Rupa J, Fahy, Brenda G, Harman, Ann E, Isaak, Robert S, Lien, Cynthia A, Macario, Alex, Menzies, Anna O, Peterson-Layne, Cathleen, Sun, Huaping, Suresh, Santhanam, Warner, David O   +11 more
core  

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications

Advanced Science, EarlyView.
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley   +1 more source

Perioperative Care of Patients at High Risk for Stroke During or After Non-cardiac, Non-neurological Surgery: 2020 Guidelines From the Society for Neuroscience in Anesthesiology and Critical Care

Journal of Neurosurgical Anesthesiology, 2020
Supplemental Digital Content is available in the text. Perioperative stroke is associated with considerable morbidity and mortality. Stroke recognition and diagnosis are challenging perioperatively, and surgical patients receive therapeutic interventions
P. Vlisides, L. Moore, M. Whalin, S. Robicsek, A. Gelb, A. Lele, G. Mashour   +6 more
semanticscholar   +1 more source