ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li+5 more
wiley +1 more source
Trends and Emerging Research Areas in Postoperative Sleep Disturbances: A Bibliometric Analysis
Wei Du, Xi Qiao, Wei Liu, Chao Li, Huiqun Jia Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, People’s Republic of ChinaCorrespondence: Huiqun Jia, The Fourth Hospital of Hebei Medical ...
Du W, Qiao X, Liu W, Li C, Jia H
doaj
Do Complexity Measures of Frontal EEG Distinguish Loss of Consciousness in Geriatric Patients Under Anesthesia? [PDF]
While geriatric patients have a high likelihood of requiring anesthesia, they carry an increased risk for adverse cognitive outcomes from its use. Previous work suggests this could be mitigated by better intraoperative monitoring using indexes defined by
Caitlin M. Drover+8 more
core +2 more sources
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei+10 more
wiley +1 more source
Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients
Yueting Chen,1,* Zuo-Jing Zhang,2,* Xiao-Feng Zhang,2 Yuan Peng,2 Zheng Jiao,1,* Jing-Xiang Wu2,* 1Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s ...
Chen Y+5 more
doaj
Supplemental peri-operative intravenous crystalloids for postoperative nausea and vomiting: an abridged Cochrane systematic review. [PDF]
We conducted a Cochrane systematic review on the effectiveness of supplemental intravenous crystalloid administration in preventing postoperative nausea and vomiting.
Bird, SJ+5 more
core
Obstructive sleep apnea as an independent predictor of postoperative delirium and pain: Protocol for an observational study of a surgical cohort [version 2; referees: 2 approved] [PDF]
Introduction: Postoperative delirium and pain are common complications in adults, and are difficult both to prevent and treat. Obstructive sleep apnea (OSA) is prevalent in surgical patients, and has been suggested to be a risk factor for postoperative ...
Arrington, Brianna+7 more
core +2 more sources
This study proposes for the first time that hepatic GSDMD plays a key protective role in sepsis. Hepatic GSDMD may release inflammatory inhibitory factors including VEGF‐B and Gremlin‐1 through pore‐forming activity to inhibit the production of inflammatory factors from macrophages, thereby alleviating the inflammatory response of septic mice ...
Yihan Qian+9 more
wiley +1 more source
Retracted: Intrathecal Pump Implantation in the Cisterna Magna for Treating Intractable Cancer Pain
Case Reports in Anesthesiology
doaj +1 more source
Air quality and employee hygiene-related behavior in a post anesthesia care unit in Thailand
Post anesthesia care units (PACU) are sanitary spaces at hospitals. Bacterial and fungal contaminants in ambient air can pose significant threats to patient recovery.
Somphorn Kampan
doaj +1 more source