Results 31 to 40 of about 2,711,128 (308)

Linalool attenuated ischemic injury in PC12 cells through inhibition of caspase‐3 and caspase‐9 during apoptosis

Food Science &Nutrition, Volume 11, Issue 1, Page 249-260, January 2023., 2023
This study indicated, for the first time, that (±) linalool and its enantiomer, (R)‐(‐) linalool protected PC12 cells against injury induced by oxygen and glucose deprivation/reoxygenation (OGD/R) via the mitigation of oxidative stress and the downregulation of Bax/Bcl‐2, caspase‐3 and caspase‐9, resulting in decreased apoptotic cell death.
Azar Hosseini, Elham Pourheidar, Arezoo Rajabian, Elham Asadpour, Hossein Hosseinzadeh, Hamid Reza Sadeghnia   +5 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

The State of Research Funding for Interventional Chronic Pain Therapies

Journal of Pain Research, 2023
Sunil Agarwal,1 Christopher Gharibo,2 Michael E Schatman2,3 1Department of Anesthesiology, Division of Pain Medicine, Emory University School of Medicine, Atlanta, GA, USA; 2Department of Anesthesiology, Perioperative Care & Pain Medicine, NYU Grossman ...
Agarwal S, Gharibo C, Schatman ME
doaj  

A nationwide assessment of hepatocellular adenoma resection: Indications and pathological discordance

Hepatology Communications, EarlyView., 2022
Abstract Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed.
Martijn P. D. Haring, Arthur K. E. Elfrink, Christiaan A. J. Oudmaijer, Paul C. M. Andel, Alicia Furumaya, Nenke de Jong, Colin J. J. M. Willems, Thijs Huits, Julie M. L. Sijmons, Eric J. T. Belt, Koop Bosscha, Esther C. J. Consten, Mariëlle M. E. Coolsen, Peter van Duijvendijk, Joris I. Erdmann, Paul Gobardhan, Robbert J. de Haas, Tjarda van Heek, Hwai‐Ding Lam, Wouter K. G. Leclercq, Mike S. L. Liem, Hendrik A. Marsman, Gijs A. Patijn, Türkan Terkivatan, Babs M. Zonderhuis, Izaak Quintus Molenaar, Wouter W. te Riele, Jeroen Hagendoorn, Alexander F. M. Schaapherder, Jan N. M. IJzermans, Carlijn I. Buis, Joost M. Klaase, Koert P. de Jong, Vincent E. de Meijer, the Dutch Benign Liver Tumor Group, R. B. Takkenberg, J. Verheij, O. M. van Delden, J. I. Erdmann, B. V. van Rosmalen, A. Furumaya, G. Kazemier, D. Ramsoekh, J. N. M. IJzermans, R. A. de Man, M. D. Doukas, M. G. Thomeer, A. J. Klompenhouwer, A. F. M. Schaapherder, M. E. Tushuizen, M. J. Coenraad, A. S. L. P. Crobach, M. C. Burgmans, S. Feshtali, M. M. E. Coolsen, M. Kramer, J. C. Beckervordersandforth, I. V. Samarska, C. van der Leij, R. Miclea, J. H. W. de Wilt, P. B. van den Boezem, E. T. T. L. Tjwa, I. Munsterman, S. Vos, S. van Koeverden, V. E. de Meijer, F. J. C. Cuperus, R. J. de Haas, E. W. Duiker, M. P. D. Haring   +70 more
wiley   +1 more source

Increased Demand for Ketamine Infusions and Associated Complexities

Journal of Pain Research, 2023
Evan Peskin,1 Jeffrey Gudin,2 Michael E Schatman3,4 1Department of Pain Management - Insight Institute of Neurosurgery & Neuroscience, Flint, MI, USA; 2Professor of Anesthesiology, Perioperative Medicine and Pain Management - University of Miami, Miller ...
Peskin E, Gudin J, Schatman ME
doaj  

Medical Cannabis: A Review from the American Society of Pain and Neuroscience

Journal of Pain Research, 2023
Natalie Strand,1 Ryan S D’Souza,2 Jay Karri,3 Hemant Kalia,4 Jackie Weisbein,5 Brian J Kassa,6 Nasir Hussain,7 Ahish Chitneni,8 Ryan R Budwany,9 Jonathan Hagedorn,2 Jason E Pope,10 Timothy R Deer,11 Dawood Sayed,12 Alaa Abd-Elsayed13 1Department of ...
Strand N, D’Souza RS, Karri J, Kalia H, Weisbein J, Kassa BJ, Hussain N, Chitneni A, Budwany RR, Hagedorn J, Pope JE, Deer TR, Sayed D, Abd-Elsayed A   +13 more
doaj  

Our Anesthesia and Pain Medicine is currently expanding into a global-scale journal

Anesthesia and Pain Medicine, 2023
journal of the Korean Society of Anesthesiologists (KSA) and represents the official journals of the following societies: the Korean Society of Neuroscience in Anesthesiology and Critical Care (KSNACC), the Korean Society for Anesthetic Pharmacology ...
H. Seo, H. Kang
semanticscholar   +1 more source

Automated Detection of Rest Disruptions in Critically Ill Patients [PDF]

2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Montreal, QC, Canada, 2020, pp. 5450-5454, 2020
Sleep has been shown to be an indispensable and important component of patients recovery process. Nonetheless, sleep quality of patients in the Intensive Care Unit (ICU) is often low, due to factors such as noise, pain, and frequent nursing care activities.
arxiv   +1 more source

Offline reinforcement learning with uncertainty for treatment strategies in sepsis [PDF]

arXiv, 2021
Guideline-based treatment for sepsis and septic shock is difficult because sepsis is a disparate range of life-threatening organ dysfunctions whose pathophysiology is not fully understood. Early intervention in sepsis is crucial for patient outcome, yet those interventions have adverse effects and are frequently overadministered.
arxiv  

Machine learning-based analysis of hyperspectral images for automated sepsis diagnosis [PDF]

arXiv, 2021
Sepsis is a leading cause of mortality and critical illness worldwide. While robust biomarkers for early diagnosis are still missing, recent work indicates that hyperspectral imaging (HSI) has the potential to overcome this bottleneck by monitoring microcirculatory alterations.
arxiv