Results 51 to 60 of about 2,711,128 (308)

Feasibility of perioperative remote monitoring of patient‐generated health data in complex surgical oncology

Journal of Surgical Oncology, Volume 127, Issue 1, Page 192-202, January 2023., 2023
Abstract Background The feasibility of remote perioperative telemonitoring of patient‐generated physiologic health data and patient‐reported outcomes in a high risk complex general and urologic oncology surgery population is evaluated. Methods Complex general surgical/urologic oncology patients wore a pedometer, completed ePROs (electronic patient ...
Laleh G. Melstrom, Xiaoke Zhou, Andreas Kaiser, Kevin Chan, Clayton Lau, Mustafa Raoof, Susanne G. Warner, Ali Zhumkhawala, Bertram Yuh, Gagandeep Singh, Yuman Fong, Virginia Sun   +11 more
wiley   +1 more source

Anesthesia in a Patient with Potocki–Lupski Syndrome

Case Reports in Anesthesiology, 2021
Introduction. Potocki–Lupski syndrome (PTLS) is a rare disease caused by the duplication of a small segment of chromosome 17 (17p11.2). The clinical presentation of this syndrome is quite variable and includes hypotonia, failure to thrive, oropharyngeal ...
Songhyun Kim, Yunhee Lim, In-Jung Jun, Byunghoon Yoo, Kye-Min Kim   +4 more
doaj   +1 more source

Decoding the Molecular Universe -- Workshop Report [PDF]

arXiv, 2023
On August 9-10, 2023, a workshop was convened at the Pacific Northwest National Laboratory (PNNL) in Richland, WA that brought together a group of internationally recognized experts in metabolomics, natural products discovery, chemical ecology, chemical and biological threat assessment, cheminformatics, computational chemistry, cloud computing ...
arxiv  

Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons [PDF]

Journal of Experimental Medicine Aug 2019, 216 (8) 1904-1924, 2019
Rheumatoid arthritis-associated joint pain is frequently observed independent of disease activity, suggesting unidentified pain mechanisms. We demonstrate that antibodies binding to cartilage, specific for collagen type II (CII) or cartilage oligomeric matrix protein (COMP), elicit mechanical hypersensitivity in mice, uncoupled from visual ...
arxiv   +1 more source

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

Advanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan, Yan Fang, Chuyun Lou, Nan Chen, Xuan Mo, Bo Jiao, Mengke Liu, Yangxi Zhao, Weichen Xu, Huixiong Xu, Haohao Yin, Yi Zhang   +11 more
wiley   +1 more source

An approach to study recruitment/derecruitment dynamics in a patient-specific computational model of an injured human lung [PDF]

arXiv, 2022
We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an anatomically accurate, spatially resolved model of respiratory system mechanics, and the relation of these dynamics
arxiv  

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

Advanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman, Taron Bashar, Alex Burton, David Marshall Clausen, Prashant Gupta, Drew K. Wolf, Jakayla Folarin‐Hines, Maria Payne, John A Rogers, Kathleen W. Meacham, Robert W. Gereau, Philipp Gutruf   +11 more
wiley   +1 more source

A Full Transformer-based Framework for Automatic Pain Estimation using Videos [PDF]

2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
The automatic estimation of pain is essential in designing an optimal pain management system offering reliable assessment and reducing the suffering of patients. In this study, we present a novel full transformer-based framework consisting of a Transformer in Transformer (TNT) model and a Transformer leveraging cross-attention and self-attention blocks.
arxiv   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

Advanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu, Chengya Huang, Xin Li, Haonan Yu, Yuefeng Xia, Kun Liu, Xingji You, Jingxiang Wu   +7 more
wiley   +1 more source

Automatic pain recognition from Blood Volume Pulse (BVP) signal using machine learning techniques [PDF]

arXiv, 2023
Physiological responses to pain have received increasing attention among researchers for developing an automated pain recognition sensing system. Though less explored, Blood Volume Pulse (BVP) is one of the candidate physiological measures that could help objective pain assessment. In this study, we applied machine learning techniques on BVP signals to
arxiv