Results 61 to 70 of about 114,126 (330)

Post-Pancreatoduodenectomy Outcomes and Epidural Analgesia: A 5-Year Single Institution Experience [PDF]

, 2019
Introduction Optimal pain control post-pancreatoduodenectomy is a challenge. Epidural analgesia (EDA) is increasingly utilized despite inherent risks and unclear effects on outcomes.
Ceppa, Eugene P., Colgate, Cameron L., Fennerty, Mitchell L., House, Michael G., Kilbane, E. Molly, Nakeeb, Attila, Schmidt, C. Max, Simpson, Rachel E., Zyromski, Nicholas J.   +8 more
core   +1 more source

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

Advanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang, Xue Jiang, Bingrui Xiong, Jiayi Chen, Xin Liu, Siyuan Wang, Bofu Li, Mian Peng, Wei Li   +8 more
wiley   +1 more source

Serious Issues in Authorship, Design, and Conclusions of JAMA Neurology Real-World Evidence Study on Spinal Cord Stimulation Outcomes and Costs as Compared to Conventional Medical Therapy

Journal of Pain Research, 2023
Timothy Deer,1 Alaa Abd-Elsayed,2 Krishnan Chakravarthy,3 Joshua M Rosenow,4 Steven Falowski,5 Erika Petersen,6 Julie Pilitsis,7 Corey Hunter,8 Dawood Sayed,9 Michael E Schatman10,11 1The Spine and Nerve Center of the Virginias, Charleston, WV, USA ...
Deer T, Abd-Elsayed A, Chakravarthy K, Rosenow JM, Falowski S, Petersen E, Pilitsis J, Hunter C, Sayed D, Schatman ME   +9 more
doaj  

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

A randomised, controlled, double blind, non-inferiority trial of ultrasound-guided fascia iliaca block vs. spinal morphine for analgesia after primary hip arthroplasty [PDF]

, 2016
We performed a single centre, double blind, randomised, controlled, non-inferiority study comparing ultrasound-guided fascia iliaca block with spinal morphine for the primary outcome of 24-h postoperative morphine consumption in patients undergoing ...
Anderson, K., Grant, A., Harrison, P., Kearns, R., Kinsella, J., Macfarlane, A., Puxty, K., Shaw, M.   +7 more
core   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Relationship Between Kyphosis and Postoperative Gastroesophageal Reflux After Proximal Gastrectomy

Annals of Gastroenterological Surgery, EarlyView.
This study examined the relationship between kyphosis and postoperative gastroesophageal reflux disease (GERD) after proximal gastrectomy using a kyphosis definition that is familiar to surgeons for preoperative assessment. Multivariate analysis revealed that kyphosis is an independent risk factor for GERD after proximal gastrectomy.
Takaomi Ozawa, Suguru Maruyama, Katsutoshi Shoda, Yoshihiko Kawaguchi, Ryo Saito, Kensuke Shiraishi, Shinji Furuya, Hidetake Amemiya, Hiromichi Kawaida, Daisuke Ichikawa   +9 more
wiley   +1 more source

Prognostic Significance of GLIM‐Defined Malnutrition in Patients With Resectable Pancreatic Adenocarcinoma Following Upfront Surgery

Annals of Gastroenterological Surgery, EarlyView.
The GLIM criteria are effective prognostic predictors in patients with resectable PDAC undergoing upfront surgery. Preoperative nutritional assessment using these criteria may contribute to determining treatment plans for resectable PDAC. ABSTRACT Aim Regarding the resectability of pancreatic adenocarcinoma (PDAC), not only anatomical factors but also ...
Takuya Mizumoto, Yoshihide Nanno, Jun Ishida, Dongha Lee, Kenji Fukushima, Shohei Komatsu, Hiroaki Yanagimoto, Sadaki Asari, Masahiro Kido, Takumi Fukumoto   +9 more
wiley   +1 more source

Safety and Efficacy of Pelvic Reinforcement Procedure for Preventing Postoperative Perineal Hernia After Robotic Abdominoperineal Resection: A Single‐Center, Retrospective Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate the safety and efficacy of pelvic reinforcement procedure (PRP) in robotic abdominoperineal resection (Ro‐APR). PRP‐ had a significantly higher rate of imaged perineal hernia (PH) (39.2% vs. 6.7%, p = 0.005) and symptomatic PH (19.6% vs.
Yoshihiro Sakai, Shunsuke Kasai, Akio Shiomi, Shoichi Manabe, Yusuke Yamaoka, Yusuke Tanaka, Takahiro Igaki, Hiroyasu Kagawa, Yusuke Kinugasa   +8 more
wiley   +1 more source

Postoperative Heart Failure with Preserved Ejection Fraction Induced by Flumazenil Administered for Remimazolam Antagonism

Case Reports in Anesthesiology, 2022
Remimazolam is an ultrashort-acting benzodiazepine intravenous anesthetic characterized by rapid awakening after anesthesia. However, the method for administering remimazolam in clinical practice remains unclear.
Keito Koh, Takeshi Omae, Sonoko Sakuraba, Masateru Kumemura, Sho Yamazaki, Hiroshi Yunoki   +5 more
doaj   +1 more source