Results 81 to 90 of about 2,711,128 (308)

History of scurvy and use of vitamin C in critical illness: A narrative review

Nutrition in Clinical Practice, Volume 38, Issue 1, Page 46-54, February 2023., 2023
Abstract In 1747, an important milestone in the history of clinical research was set, as the Scottish surgeon James Lind conducted the first randomized controlled trial. Lind was interested in scurvy, a severe vitamin C deficiency which caused the death of thousands of British seamen.
Ellen Dresen, Zheng‐Yii Lee, Aileen Hill, Quirin Notz, Jayshil J. Patel, Christian Stoppe   +5 more
wiley   +1 more source

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

The American Society of Pain and Neuroscience (ASPN) Practical Guidelines to Study Design and Scientific Manuscript Preparation in Neuromodulation

Journal of Pain Research, 2021
Yashar Eshraghi,1– 3 Krishnan Chakravarthy,4,5 Natalie H Strand,6 Prasad Shirvalkar,7 Nathaniel M Schuster,4 Rany T Abdallah,8 Ricardo Vallejo,9,10 Dawood Sayed,11 David Kim,11 Chong Kim,12 Kathleen Meacham,13 Timothy Deer14,15 On Behalf of ...
Eshraghi Y, Chakravarthy K, Strand NH, Shirvalkar P, Schuster NM, Abdallah RT, Vallejo R, Sayed D, Kim D, Kim C, Meacham K, Deer T   +11 more
doaj  

Deep Reinforcement Learning for Optimal Critical Care Pain Management with Morphine using Dueling Double-Deep Q Networks [PDF]

arXiv, 2019
Opioids are the preferred medications for the treatment of pain in the intensive care unit. While undertreatment leads to unrelieved pain and poor clinical outcomes, excessive use of opioids puts patients at risk of experiencing multiple adverse effects.
arxiv  

Axonal profiling of the common fibular nerve and its branches: Their functional composition and clinical implications

Clinical Anatomy, EarlyView.
Abstract The articular branch (Arb) from the common fibular nerve (CFN) plays a pivotal role in procedures such as genicular nerve blocks since it extensively innervates the anterolateral knee joint. It remains unclear whether the Arb can be classified as purely sensory, and understanding its axonal composition is critical to prevent muscle weakness ...
Taeyeon Kim, Tae‐Hyeon Cho, Shin Hyung Kim, Hun‐Mu Yang   +3 more
wiley   +1 more source

Does immediate skin‐to‐skin contact at caesarean sections promote uterine contraction and recovery of the maternal blood haemoglobin levels? A randomized clinical trial

Nursing Open, Volume 10, Issue 2, Page 649-657, February 2023., 2023
Abstract Aim We analysed whether immediate skin‐to‐skin contact between the healthy newborn and the mother after a caesarean section has a modulatory role on postpartum haemorrhage and uterine contraction. Design Unblinded, randomized clinical trial, simple random sampling, conducted in women undergoing caesarean sections.
José Miguel Pérez‐Jiménez, Manuel Luque‐Oliveros, Diego Gonzalez‐Perez, Adriana Rivera‐Sequeiros, Cleofás Rodriguez‐Blanco   +4 more
wiley   +1 more source

Anatomical Study of the Retrodural Space of Okada in the Cervical Region: 3D Micro‐CT Findings

Clinical Anatomy, EarlyView.
ABSTRACT The retrodural space of Okada (RSO) is a potential space located posterior to the ligamentum flavum. It can complicate epidural injections owing to its communication with the epidural space and facet joints. The purpose of this study was to clarify the anatomical structures of the cervical RSO and adjacent ligamentous tissues in cadavers ...
Tae‐Hyeon Cho, Byongnam Jun, Shin Hyung Kim, Hun‐Mu Yang   +3 more
wiley   +1 more source

Comparing Analgesic Efficacy of Regional Block Techniques After Laparoscopic Liver Resection: In Reply [Response to Letter]

Journal of Pain Research, 2022
RyungA Kang, Justin Sangwook Ko Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaCorrespondence: Justin Sangwook Ko, Department of Anesthesiology and Pain Medicine, Samsung ...
Kang R, Ko JS
doaj  

VoPo leverages cellular heterogeneity for predictive modeling of single-cell data

Nature Communications, 2020
Single-cell technologies are increasingly prominent in clinical applications, but predictive modelling with such data in large cohorts has remained computationally challenging.
Natalie Stanley, Ina A. Stelzer, Amy S. Tsai, Ramin Fallahzadeh, Edward Ganio, Martin Becker, Thanaphong Phongpreecha, Huda Nassar, Sajjad Ghaemi, Ivana Maric, Anthony Culos, Alan L. Chang, Maria Xenochristou, Xiaoyuan Han, Camilo Espinosa, Kristen Rumer, Laura Peterson, Franck Verdonk, Dyani Gaudilliere, Eileen Tsai, Dorien Feyaerts, Jakob Einhaus, Kazuo Ando, Ronald J. Wong, Gerlinde Obermoser, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Brice Gaudilliere, Nima Aghaeepour   +29 more
doaj   +1 more source

CYP3A Mediated Ketamine Metabolism is Severely Impaired in Liver S9 Fractions from Aging Sprague Dawley Rats [PDF]

arXiv, 2015
Ketamine is widely used in veterinary medicine and in medicine. Ketamine is metabolized to its active metabolite norketamine principally by liver CYP3A. Drug metabolism alterations during aging have severe consequences particularly in anesthesiology and very few studies on older animals were conducted for ketamine. The objective of the present study is
arxiv