Results 261 to 270 of about 4,827,901 (330)

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

Advanced Science, EarlyView.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang, Yabing Zhang, Zhiye Guo, He Ren, Weiyi Hu, Qingping Yao, Yunlong Huo, Yingxin Qi, Kai Huang   +8 more
wiley   +1 more source

The quest for comfort: Exploring the effectiveness of and patient satisfaction with needleless anesthesia in dental procedures. [PDF]

J Conserv Dent Endod
Singh S, Koshy M.
europepmc   +1 more source

Glucose‐Responsive and Analgesic Gel for Diabetic Subcutaneous Abscess Treatment by Simultaneously Boosting Photodynamic Therapy and Relieving Hypoxia

Advanced Science, EarlyView.
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang, Honglin An, Jianfeng Chu, Shiqi Ke, Jing Ke, Yiman Qiu, Jieping Zhang, Hanqi Zhu, Jiahui Lin, Minguang Yang, Dongliang Yang, Xuejiao Song, Weilin Liu   +12 more
wiley   +1 more source

Narrative Review on Postoperative Pain Management Following Spine Surgery. [PDF]

Neurospine
Yu C, Madsen M, Akande O, Oh MY, Mattie R, Lee DW.   +5 more
europepmc   +1 more source

Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain

Advanced Science, EarlyView.
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang, Xiuru Ji, Yu Sun, Han Wang, Ting Wang, Tao Luo, Yanyong Cheng, Jia Yan, Dalong Ni, Hong Jiang   +9 more
wiley   +1 more source

Brainstem anesthesia after retrobulbar block under brief analgosedation: Evidence for the underlying patho-mechanism. [PDF]

Eur J Ophthalmol
Thomasius MA, Menghini M, Breckwoldt J.
europepmc   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Serratus Anterior Plane Block for Pain Management After Video-Assisted Thoracoscopic Surgeries: A Narrative Review. [PDF]

Medicina (Kaunas)
Ahmadzadeh S, Serio MA, Nguyen A, Dethloff DR, Robichaux C, Mosieri CN, Shekoohi S, Kaye AD.   +7 more
europepmc   +1 more source

Effective anesthesia management for super obesity-related compartment syndrome with ultrasound and Doppler guidance: A different strategy. [PDF]

Saudi J Anaesth
Gentili L, Guerriero G, Nania F, Angeletti C.   +3 more
europepmc   +1 more source

Comparison of Quadratus Lumborum Block and Rectus Sheath Block for Postoperative Analgesia in Single-Port Laparoscopic Adnexal Surgery: A Randomized Controlled Trial. [PDF]

Medicina (Kaunas)
Kim D, Bang S, Chung J, Lee Y, Shin HJ, Park Y.   +5 more
europepmc   +1 more source