Results 51 to 60 of about 161,077 (300)
Machine‐Learning‐Aided Advanced Electrochemical Biosensors
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan+9 more
wiley +1 more source
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang+25 more
wiley +1 more source
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen+3 more
wiley +1 more source
Anesthesia management of a parturient with meningioma underwent elective Cesarean section
The occurrence of primary intracranial tumors in pregnancy is an extremely rare event. Symptoms of a brain tumor include nausea, vomiting, headache, visual disturbances and seizures which mimic symptoms of pregnancy-related hyperemesis or eclampsia.
Susilo Chandra
doaj +1 more source
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang+16 more
wiley +1 more source
Anesthetic management of patients having immune thrombocytopenic purpura (ITP) remains a challenge for the anesthesiologist. Surgeries such as knee arthroplasty are associated with significant bleeding.
Tasneem Dhansura+3 more
doaj +1 more source
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu+20 more
wiley +1 more source
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich+8 more
wiley +1 more source
Perioperative Anesthetic Management in Term Pregnant Women with Idiopathic Pulmonary Hypertension
Introduction: Pulmonary arterial hypertension is a disease with low incidence in the pregnant woman, although it brings about high mortality once presented.
Sergio Felipe Dávila Cabrera+4 more
doaj
3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee+10 more
wiley +1 more source