In vivo whole-cell recording from morphologically identified mouse superior colliculus neurons [PDF]
STAR Protocols 4 (2023) 101963, 2022 In vivo whole-cell recording when combined with morphological characterization after biocytin labeling is a powerful technique to study subthreshold synaptic processing in cell-type-identified neuronal populations. Here, we provide a step-by-step procedure for performing whole-cell recordings in the superior colliculus of urethane-anesthetized mice, a ...
arxiv +1 more source
anesthetic: nested sampling visualisation [PDF]
Journal of Open Source Software, 2019, 4(37), 1414, 2019 anesthetic is a Python package for processing nested sampling runs, and will be useful for any scientist or statistician who uses nested sampling software. anesthetic unifies many existing tools and techniques in an extensible framework that is intuitive for users familiar with the standard Python packages, namely NumPy, SciPy, Matplotlib and pandas.
arxiv +1 more source
The free energy of biomembrane and nerve excitation and the role of anesthetics [PDF]
BBA - Biomembranes 1860 (2018) 2145-2153, 2018 In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference necessary to induce a phase transition in the nerve membrane.
arxiv +1 more source
A comparison of retrobulbar and two peribulbar regional anesthetic techniques in dog cadavers [PDF]
Veterinary Anaesthesia and Analgesia, 2017 To compare injectate distribution and likelihood of regional anesthesia to the orbit following retrobulbar (RB) or peribulbar (PB) injections in dog cadavers.Randomized, masked study.Twenty-four dog cadavers (aged 5.5-17 years, 2.0-36.3 kg).Orbits underwent one of three injection techniques with bupivacaine 0.5% and iohexol (1:1): ventrolateral RB ...
Shilo-Benjamini, Yael +5 more
openaire +3 more sources
Ketamine-Medetomidine General Anesthesia Occurs With Alternation of Cortical Electrophysiological Activity Between High and Low Complex States [PDF]
arXiv, 2022 Anesthetic agents are known to induce a range of alterations in cortical electrophysiological activity, such as the rise of signature patterns, changes in statistical properties, and altered dynamic behavior of neural records. Plenty of methods can be used to monitor these changes, among them complexity metrics demonstrated to have the power to ...
arxiv
Macaque's Cortical Functional Connectivity Dynamics at the Onset of Propofol-Induced Anesthesia [PDF]
arXiv, 2021 Propofol, when administered for general anesthesia, induces oscillatory dynamic brain states that are thought to underlie the drug's pharmacological effects. Despite the elucidation of propofol's mechanisms of action at the molecular level, its effects on neural circuits and overall cortical functioning, which eventually lead to unconsciousness, are ...
arxiv
Automatic Ultrasound Image Segmentation of Supraclavicular Nerve Using Dilated U-Net Deep Learning Architecture [PDF]
arXiv, 2022 Automated object recognition in medical images can facilitate medical diagnosis and treatment. In this paper, we automatically segmented supraclavicular nerves in ultrasound images to assist in injecting peripheral nerve blocks. Nerve blocks are generally used for pain treatment after surgery, where ultrasound guidance is used to inject local ...
arxiv
Characterization of the Community Structure of Large-Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]
arXiv, 2016 One of the main goals of neuroscience is to understand how an organism's cognitive capacities or physiological states are potentially related to brain activities that involve the interaction of multiple brain structures and cortical areas. A key feature of functional brain networks is that they are modularly structured, and this modular architecture is
arxiv
Characterization of Large-Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]
arXiv, 2016 Several experiments provide evidence that specialized brain regions functionally interact and reveal that the brain processes and integrates information in a specific and structured manner. Networks can be applied to model brain functional activities, providing means to characterize and quantify this structured form of organization.
arxiv
Nerves and Anesthesia: A physics perspective on medicine [PDF]
Anestezjologia i Ratownictwo 2014; 8: 252-263, 2014 We present a recent theory for nerve pulse propagation and anesthesia and argue that both nerve activity and the action of anesthetics can be understood on the basis of simple physical laws. It was found experimentally that biological membranes melt from a solid state to a liquid state just below physiological temperature. Such melting processes have a
arxiv