Results 91 to 100 of about 192,111 (346)

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou   +13 more
wiley   +1 more source

Adding metoclopramide to lidocaine for intravenous regional anesthesia in trauma patients

open access: yesAdvanced Biomedical Research, 2014
Background: Metoclopromide have local anesthetic properties. The main object of performing the present study was to evaluate the analgesic effect of metoclopromide 10 mg when added to lidocaine for intravenous regional anesthesia (IVRA) of upper ...
Mohammadreza Safavi   +2 more
doaj   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

open access: yesAdvanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger   +17 more
wiley   +1 more source

The applications of sub-Tenon's anaesthesia for canine ophthalmic surgery : a thesis presented in fulfilment of the requirements for the degree of Master of Veterinary Science (MVSc) at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2016
Sub-Tenon's anaesthesia is an indispensable anaesthetic technique in human ophthalmic surgery. It produces highly effective regional anaesthesia and has a significantly lower complication rate than the previously used peribulbar and retrobulbar ...
Bayley, Kellam David
core  

Effect of adding 8 milligrams ondansetron to lidocaine for Bier′s block on post-operative pain

open access: yesAdvanced Biomedical Research, 2013
Background: Ondansetron has analgesic properties. The aim of the present study was to assess the analgesic effect of 8 mg ondansetron when added to lidocaine for intravenous regional anesthesia (IVRA).
Azim Honarmand   +2 more
doaj   +1 more source

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

open access: yesAdvanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang   +13 more
wiley   +1 more source

The effect of anesthetic technique for transvaginal ultrasound-guided oocyte retrieval on reproductive outcomes: A systematic review and meta-analysis

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2015
The effects of various anesthetic techniques used for transvaginal ultrasound-guided oocyte retrieval (TUGOR) on reproductive outcomes remain controversial.
Bharatram Vasudevan   +5 more
doaj   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Designing the ideal perioperative pain management plan starts with multimodal analgesia. [PDF]

open access: yes, 2018
Multimodal analgesia is defined as the use of more than one pharmacological class of analgesic medication targeting different receptors along the pain pathway with the goal of improving analgesia while reducing individual class-related side effects ...
Mariano, Edward R., Schwenk, Eric S.
core   +1 more source

Regional Analgesia for Cesarean Delivery: A Narrative Review Toward Enhancing Outcomes in Parturients

open access: yesJournal of Pain Research, 2023
Matthew Silverman,1 Nicholas Zwolinski,1 Ethan Wang,2 Nishita Lockwood,1 Michael Ancuta,1 Evan Jin,1 Jinlei Li1 1Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA; 2Yale University School of Medicine, New Haven, CT ...
Silverman M   +6 more
doaj  

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