Results 151 to 160 of about 548,111 (319)

Amyloid‐β Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord

open access: yesGlia, EarlyView.
Amyloid‐β peptide induces early oligodendrocyte differentiation and dorsal myelination in the zebrafish larvae spinal cord. Pan‐PKC inhibitor Gö6983 restores the aforementioned alterations in oligodendrocytes and myelin. ABSTRACT Soluble forms of amyloid‐β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and myelin ...
Uxue Balantzategi   +7 more
wiley   +1 more source

UEG and EAES rapid guideline: Update systematic review, network meta‐analysis, CINeMA and GRADE assessment, and evidence‐informed European recommendations on surgical management of GERD

open access: yesUnited European Gastroenterology Journal, Volume 10, Issue 9, Page 983-998, November 2022., 2022
Abstract Background There are several options for the surgical management of GERD in adults. Previous guidelines and systematic reviews have compared the effects of total fundoplication versus pooled effects of different techniques of partial fundoplication.
Sheraz Markar   +16 more
wiley   +1 more source

Hippocampal Astrocyte Morphology Follows an Unexpected Trajectory With Age in a Transgenic Rodent Model of Tauopathy

open access: yesGlia, EarlyView.
ABSTRACT Individual protoplasmic astrocytes have very complex and diverse spongiform shapes. The morphological diversity of astrocytes is determined by the structural and functional interactions of the astrocyte with its microenvironment. When faced with pathological conditions, astrocytes reorganize their morphology.
Emma Augustin   +20 more
wiley   +1 more source

Performance evaluation of electrode design and material for a large animal electrical impedance tomography belt

open access: yesVeterinary Record, Volume 191, Issue 12, 17–31 December 2022., 2022
Abstract Background Electrical impedance tomography (EIT) produces lung ventilation images via a thoracic electrode belt. Robust electrode design and material, providing low electrode skin contact impedance (SCI), is needed in veterinary medicine. The aim of this study was to compare three EIT electrode designs and materials.
Olivia Brabant   +5 more
wiley   +1 more source

The Future Hospital in Global Health Systems: The Future Hospital as an Entity

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Health care is changing rapidly. Hospitals are, and will remain, an essential setting to deliver it. We discuss how to maximise the benefits of hospitals in the future in different geographic and health system settings, highlighting a series of cross‐cutting issues.
N. J. Sebire   +10 more
wiley   +1 more source

Research progress on the mechanisms of pain empathy

open access: yesIbrain, EarlyView.
This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu   +5 more
wiley   +1 more source

Effect of temperature‐responsive hydrogel on femoral and sciatic nerve blocks using bupivacaine in Beagle dogs

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 91-97, January 2023., 2023
Recent developed temperature‐responsive hydrogel, PF‐72®, was applied to extend the duration of regional anesthesia of the pelvic limb using bupivacaine. Significantly longer nerve block duration was confirmed when bupivacaine was used in combination with PF‐72® than it was used alone.
Jiyoung Kim   +8 more
wiley   +1 more source

Proteomic Learning of Gamma-Aminobutyric Acid (GABA) Receptor-Mediated Anesthesia [PDF]

open access: yesarXiv
Anesthetics are crucial in surgical procedures and therapeutic interventions, but they come with side effects and varying levels of effectiveness, calling for novel anesthetic agents that offer more precise and controllable effects. Targeting Gamma-aminobutyric acid (GABA) receptors, the primary inhibitory receptors in the central nervous system, could
arxiv  

Informed consent and ethical issues pertaining to female sterilization—Scoping review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Female sterilization, a safe, permanent method of contraception that blocks the fallopian tubes, has been in use since the 19th century. The procedure necessitates informed consent, a critical step that has been marred by reports of forced sterilization since World War II. These incidents often stem from inadequate consent processes
Sharol Malekobane Maila   +2 more
wiley   +1 more source

Cesarean section: One procedure, varied techniques. Detailed observations of 1013 first cesarean sections in a tertiary hospital in Ghana

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Cesarean sections (CS) are among the most performed surgical procedures in the world. Small variations in surgical techniques could have a significant impact on a global scale, for example, in postoperative complications. In the present study we aimed to observe and audit every single step used during first time CS.
Kwaku Asah‐Opoku   +9 more
wiley   +1 more source

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