Results 51 to 60 of about 18,240 (263)

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Mistura com excesso enantiomérico de 50% de bupivacaína (S75:R25) hiperbárica para procedimentos cirúrgicos infra-umbilicais: estudo com diferentes volumes Mezcla con exceso enantiomérico de 50% de bupivacaína (S75:R25) hiperbárica para procedimientos quirúrgicos infraumbilicales: estudio con diferentes volúmenes 50% enantiomeric excess hyperbaric bupivacaine (S75:R25) for infraumbilical surgeries: study with different volumes

Revista Brasileira de Anestesiologia, 2009
JUSTIFICATIVA E OBJETIVOS: A bupivacaína hiperbárica comercialmente utilizada apresenta-se como forma racêmica. No Brasil, a bupivacaína em excesso enantiomérico de 50% (S75:R25) foi lançada somente na forma isobárica. O objetivo deste estudo foi avaliar
Luiz Eduardo Imbelloni, José Antônio Cordeiro   +1 more
doaj   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Meningite após técnica combinada para analgesia de parto: relato de caso Meningitis después de técnica combinada para analgesia de parto: relato de caso Meningitis after combined spinal-epidural analgesia for labor: case report

Revista Brasileira de Anestesiologia, 2002
JUSTIFICATIVA E OBJETIVOS: Meningite é uma complicação grave em anestesia regional, embora rara de ocorrer. O objetivo deste relato é mostrar um caso de uma paciente que evoluiu com meningite após realização de analgesia de parto pela técnica combinada ...
Carlos Escobar Vásquez, Raquel da Rocha Pereira, Tomio Tomita, Antonio Bedin, Renato Almeida Couto de Castro   +4 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Anestesia em paciente com doença de Steinert: relato de caso Anestesia en paciente con enfermedad de Steinert: relato de caso Anesthesia in a patient with Steinert disease: case report

Revista Brasileira de Anestesiologia, 2006
JUSTIFICATIVA E OBJETIVOS: A doença de Steinert é a forma de distrofia muscular mais comum no adulto. Devido ao seu caráter multissistêmico o manuseio perioperatório é um desafio ao anestesiologista.
Fabiano Souza Araújo, Roberto Cardoso Bessa Júnior, Carlos Henrique Viana de Castro, Marcos Guilherme Cunha Cruvinel, Dalton Santos   +4 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Efeito da adição de clonidina subaracnóidea à solução anestésica de sufentanil e bupivacaína hiperbárica ou hipobárica para analgesia de parto Efecto de la adición de clonidina subaracnoidea a la solución anestésica de sufentanil y bupivacaína hiperbárica o hipobárica para la analgesia de parto Effects of the addition of subarachnoid clonidine to the anesthetic solution of sufentanil and hyperbaric or hypobaric bupivacaine for labor analgesia

Revista Brasileira de Anestesiologia, 2008
JUSTIFICATIVA E OBJETIVOS: Adição de clonidina subaracnóidea (±-agonista) prolonga a ação analgésica da combinação sufentanil e bupivacaína isobárica em analgesia combinada para o trabalho de parto ¹.
Thaís Cristina Tebaldi, Luíz Marcelo Sá Malbouisson, Mario. M Kondo, Mônica M. S. C. Cardoso   +3 more
doaj   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source