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Pharmacology of Inhalational Anesthetics
2010Learn the pharmacokinetic factors affecting the rate of induction and emergence with inhalational anesthetics Understand the concept of Minimum Alveolar Concentration (MAC) Know the key characteristics of the four most commonly used inhalational agents (nitrous oxide, isoflurane, desflurane, sevoflurane)
Jerome M. Adams, John W. Wolfe
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Inhaled anesthetics: an historical overview
Best Practice & Research Clinical Anaesthesiology, 2005Inhalational agents have played a pivotal role in anesthesia history. The first publicly demonstrated anesthetic of the modern era, diethyl ether, was an inhalational anesthetic. The attributes of a good agent, ability to rapidly induce anesthesia, with limited side effects has led research efforts for over a hundred and fifty years.
Francis X. Whalen +2 more
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Safety of Intravenous and Inhalation Anesthetics
20139.2 Determination of Safety of Inhalation Anesthetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 9.2.1 General Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 9.2.2 Safety Margin of Inhalation Anesthetics . . . . . . . . . .
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Congenital anomalies and inhalation anesthetics
The Journal of the American Dental Association, 1976Nitrous oxide and halothane, alone and in combination, have been repeatedly shown to cause fetal anomalies and increased fetal death rates in experimental animals. Epidemiologic studies dealing with pregnant operating room personnel who were chronically exposed to trace amounts of nitrous oxide and halothane have indicated an increased number of ...
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A History of Inhaled Anesthetics [PDF]
, 2014 Valerius Cordus synthesized diethyl ether in 1540 and shortly thereafter Theophrastus Bombastus von Hohenheim (Paracelsus) noted that it could diminish pain. Priestley synthesized nitrous oxide in 1774, and in 1800, Davy found that it decreased pain and suggested its use for surgery.
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Fluorinated Inhalation Anesthetics
1994No class of chemical compounds has contributed more toward the elimination of hospital trauma than anesthetics. These drugs have changed the operating room from a chamber of horrors to a place where medical care is provided in a tranquil atmosphere to some 50 million patients every year.
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