Results 271 to 280 of about 168,620 (342)

Research progress of rebound pain after nerve block in arthroscopic rotator cuff repair. [PDF]

Front Med (Lausanne)
Yang X, Yang Y, Qin S, Chen Y.
europepmc   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Characteristics and Outcomes of Patients Receiving Volatile Anesthetics in Near-Fatal Asthma: A Retrospective Observational Cohort Study. [PDF]

Crit Care Explor
Remmington C, Camporota L, Taylor D, Sousa A, Sanderson B, Glover G.   +5 more
europepmc   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Comparison of subcostal transversus abdominis block with intraperitoneal instillation of bupivacaine and dexmedetomidine for pain relief after laparoscopic cholecystectomy, randomized double blinded controlled study. [PDF]

BMC Anesthesiol
El Sabour AIA, Youssef HA, Ismail EA, Ahmed DH.   +3 more
europepmc   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Editorial: Understanding anaesthetic effects on aquatic animals. [PDF]

Front Vet Sci
Félix L, Valentim AM, Venâncio C.
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Opiod-free anesthesia: the importance of evidence synthesis despite heterogeneity. [PDF]

J Anesth Analg Crit Care
Tripodi VF, Sardo S, Ippolito M, Cortegiani A.   +3 more
europepmc   +1 more source

EVALUATION OF THE OPERATIVE AND ANESTHETIC RISK FOR PATIENTS WITH ULCERATIVE GASTRODUODENAL BLEEDINGS

, 2014
С. Н. Потахин, V. I. Razumovsky
openalex   +1 more source