Results 291 to 300 of about 152,192 (377)

An Anticoagulant Coating Based on a Block Phosphocholine Copolymer for Potential Applications in Blood Contact Devices

open access: yesAdvanced Materials Interfaces, EarlyView.
Anticoagulant properties are critical for blood‐compatible materials, and anticoagulant coatings are a common key issue for blood‐contacting medical devices. In this study, a block copolymer poly(2‐methacrylenoxyethyl phosphocholine‐b‐glycidyl) (PMPC‐b‐GMA) is synthesized, using reversible addition‐fragmentation chain transfer polymerization (RAFT) and
Xinli Lu   +6 more
wiley   +1 more source

A Flexible‐Substrate 5‐µm‐Diameter Needle Electrode: Minimizing Neuronal Death and Enabling Year‐Long Neural Recording

open access: yesAdvanced Materials Interfaces, EarlyView.
An electrophysiological recording technology that uses a 5‐µm‐diameter microneedle electrode device is presented. Due to the remarkable small dimension of the microneedle, the electrode provides minimal invasive neural recording in a mouse brain and enables long‐term recording exceeding the year‐long duration.
Hinata Sasaki   +6 more
wiley   +1 more source

Assessing the Safety Margin for Micromotion‐Induced Strain at Electrode–Tissue Interface: A Finite Element Analysis via COMSOL

open access: yesAdvanced Materials Interfaces, EarlyView.
Brain movement significantly impacts the biocompatibility of neural probes due to continuous strain on neural tissue. This study examines strain profiles across various brain models and movement types, challenging the 5% damage threshold at the electrode–tissue interface.
Ali Sharbatian   +3 more
wiley   +1 more source

Ultra‐Flexible µ‐ECoG Arrays Based on PEDOT:PSS Micropillars

open access: yesAdvanced Materials Interfaces, EarlyView.
This work demonstrates an efficient procedure for fabricating ultra‐flexible neural interfaces endowed with micropatterned microelectrodes to increase surface area and characterized by extremely low impedance values to enable high‐quality recordings. The home‐built device has been shown to record somatosensory evoked potentials in vivo with exceptional
Alice Lunghi   +6 more
wiley   +1 more source

Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design

open access: yesAdvanced Materials Technologies, EarlyView.
Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo   +6 more
wiley   +1 more source

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