Results 301 to 310 of about 152,192 (377)

Sevoflurane-Associated Acute Liver Injury in Renal Transplantation and Review of Literature. [PDF]

Case Rep Anesthesiol
Gani I, Moin N, Fallah J, Mirza A.
europepmc   +1 more source

Nanoparticles Combining Host‐Directed Therapeutics and Antibiotics to Boost Bacterial Killing and Overall Survival of Zebrafish Embryos Infected with Mycobacterium Marinum

Advanced Therapeutics, EarlyView.
This study investigates the combination of host‐directed therapeutics (HDT) with antibiotics in a single polymeric micelle based on polypept(o)ides for the therapy of Mycobacterium tuberculosis (Mtb) and ‐marinum (Mm) infections. When the HDT and antibiotic are co‐encapsulated, it significantly reduces bacterial burden in cells and improves overall ...
Gabriela Schäfer, Dongdong Bi, Federico Fenaroli, Andrew M. Thompson, Anno Saris, Matthias Barz   +5 more
wiley   +1 more source

Bilateral Serratus Plane Block in a Critically Ill, Mechanically Ventilated Patient with Multiple Rib Fractures Due to Severe Thoracic Trauma: Case Report and Literature Review. [PDF]

J Clin Med
Baccoli F, Brunoni B, Zadek F, Papoff A, Paveri L, Torrano V, Fumagalli R, Langer T.   +7 more
europepmc   +1 more source

Antibiotic–Polycationic Peptide Conjugation as an Effective Strategy to Overcome Daptomycin Resistance

Advanced Therapeutics, EarlyView.
Antimicrobial resistance necessitates the development of new antibiotics with “resistance‐breaking” properties. In this study, conjugation of polycationic peptides is proven to represent a versatile strategy for the fast and affordable reactivation of daptomycin.
Sari Rasheed, Florian Umstätter, Eric Mühlberg, Barbro Beijer, Tobias Hertlein, Karel D. Klika, Christian Kleist, Julia Werner, Cornelius Domhan, Mara Bingel, Anna Müller, Marvin Rausch, Stefan Zimmermann, Knut Ohlsen, Uwe Haberkorn, Marcus Koch, Markus Bischoff, Tanja Schneider, Rolf Müller, Jennifer Herrmann, Walter Mier, Philipp Uhl   +21 more
wiley   +1 more source

A Flexible Interpenetrated Diamondoid Metal-Organic Framework with Aromatic-Enriched Channels as a Preconcentrator for the Detection of Fluorinated Anesthetics. [PDF]

Chem Mater
Marchetti D, Riboni N, Inge AK, Cheung O, Gemmi M, Dalcanale E, Bianchi F, Massera C, Pedrini A.   +8 more
europepmc   +1 more source

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

Advanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf, Ben S. Ou, Ye Eun Song, Joshua J. Carter, Jerry Yan, Carolyn K. Jons, Christopher O. Barnes, Eric A. Appel   +7 more
wiley   +1 more source

Anesthesia management using remimazolam for coronary artery bypass grafting and aortic valve replacement in a patient with severe cardiac dysfunction: A case report. [PDF]

SAGE Open Med Case Rep
Sagawa T, Ishida Y, Sasaki T, Hosokawa M, Bito K, Oe K.   +5 more
europepmc   +1 more source

The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ

Advanced Science, EarlyView.
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo, Biao Huang, Ping Xu, Hao Wang, Baozhen Zhang, Li Lin, Jiujiang Liao, Mingyu Hu, Xiyao Liu, Jiayu Huang, Yong Fu, Mark D. Kilby, Rodney E. Kellems, Xiujun Fan, Yang Xia, Philip N. Baker, Hongbo Qi, Chao Tong   +17 more
wiley   +1 more source

Reply to "volatile anaesthetics for ICU sedation: beyond hypnosis?": A comment on "volatile anesthetics for lung- and diaphragm-protective sedation". [PDF]

Crit Care
Müller-Wirtz LM, Schultz MJ, Meiser A.
europepmc   +1 more source

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

Advanced Science, EarlyView.
Wenxiang Meng and colleagues delve into the molecular mechanisms underlying curcumin's modulation of RNA post‐transcriptional N (6)‐methyladenosine (m6A) modification. It is found that curcumin interacts with the Z1‐type protein tyrosine phosphatase receptor (PTPRZ1), maintaining its enzymatic activity and thus regulating the phosphorylation of the m6A‐
Ninan Zhang, Ruifan Lin, Wenya Gao, Honglin Xu, Yuejia Li, Xiahe Huang, Yingchun Wang, Xianghong Jing, Wenxiang Meng, Qi Xie   +9 more
wiley   +1 more source