Results 341 to 350 of about 302,831 (404)

Dexmedetomidine induces immunogenic cancer cell death and sensitizes tumors to PD-1 blockade. [PDF]

J Immunother Cancer
Zhao L, Liu P, Sauvat A, Carnet Le Provost K, Liu J, Checcoli A, Pol J, Kepp O, Kroemer G, Bezu L.   +9 more
europepmc   +1 more source

Genetic Variation and Sex-Based Differences: Current Considerations for Anesthetic Management. [PDF]

Curr Issues Mol Biol
DiMaria S, Mangano N, Bruzzese A, Bartula B, Parikh S, Costa A.   +5 more
europepmc   +1 more source

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Single-dose local anesthetics exhibit a type-, dose-, and time-dependent chondrotoxic effect on chondrocytes and cartilage: a systematic review of the current literature

Knee Surgery, Sports Traumatology, Arthroscopy, 2018
Peter Cornelius Kreuz
exaly   +2 more sources

Local Anesthetics

Veterinary Clinics of North America: Large Animal Practice, 1981
Local anesthetics are used in a wide range of clinical situations to prevent acute pain and to stop or ameliorate pain produced by cancer or pain associated with chronic painful conditions. Knowledge of the pharmacology of local anesthetics is essential for their safe use and selection of specific agents to achieve intended goals.Local anesthetics are ...
J. Descotes, J.Cl. Evreux
openaire   +4 more sources

Local Anesthetics

Journal of PeriAnesthesia Nursing, 2007
Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. This chapter, on the analgesic aspects of local anesthetics, reviews their broad actions that affect many different molecular targets and disrupt their functions in pain processing.
F, Yanagidate, G R, Strichartz
openaire   +5 more sources

Injectable Anesthetics and Anesthetic Adjuncts

Veterinary Clinics of North America: Equine Practice, 1987
The purpose of this article is to review the use of selected anesthetics and anesthetic adjuncts in horses. Emphasis is placed on the pharmacologic bases of their use.
John C. Thurmon, John C. Thurmon, G. John Benson, G. John Benson   +3 more
openaire   +3 more sources

Chondrotoxic Effects of Local Anesthetics on Human Knee Articular Cartilage: A Systematic Review

PM & R : the journal of injury, function, and rehabilitation, 2019
To review the current literature on the effects of intraarticular local anesthetics on human knee articular cartilage.
P. Jayaram, D. Kennedy, P. Yeh, J. Dragoo   +3 more
semanticscholar   +1 more source

Design, Synthesis, and Evaluation of Novel 2,6-Disubstituted Phenol Derivatives as General Anesthetics.

Journal of Medicinal Chemistry, 2017
A novel series of optically active 2,6-disubstituted alkylphenols with improved anesthetic profiles compared to widely used propofol were synthesized.
Linlin Qin, L. Ren, Songlin Wan, Guoliang Liu, Xinfeng Luo, Zhenhong Liu, Fangqiong Li, Yan Yu, Jianyu Liu, Yonggang Wei   +9 more
semanticscholar   +1 more source

Anesthetics act in quantum channels in brain microtubules to prevent consciousness.

Current Topics in Medicinal Chemistry, 2015
The mechanism by which anesthetic gases selectively prevent consciousness and memory (sparing non-conscious brain functions) remains unknown. At the turn of the 20(th) century Meyer and Overton showed that potency of structurally dissimilar anesthetic ...
T. Craddock, S. Hameroff, A. Ayoub, M. Klobukowski, J. Tuszynski   +4 more
semanticscholar   +1 more source

Choice of anesthetics

Anesthesiology Clinics of North America, 2004
The choice of anesthetics for vascular surgical patients is not only determined by the kind and extent of the surgical procedure but also by patient comorbidities. Frequently, patients have a history of hypertension, peripheral vascular and coronary artery disease,cerebrovascular disease, and renal impairment.
Cosmin Guta, Pieter van der Starre
openaire   +3 more sources