Results 211 to 220 of about 95,739 (341)

Specific K-ras2 Mutations in Human Sporadic Colorectal Adenomas Are Associated with DNA Near-Diploid Aneuploidy and Inhibition of Proliferation [PDF]

, 1998
Walter Giaretti, Anna Rapallo, Elio Geido, Andrea Sciutto, Domenico Franco Merlo, Mauro Risio, Francesco Paolo Rossini   +6 more
openalex   +1 more source

Targeting ARPC1B+ Cancer Stem Cells to Sensitise Pancreatic Cancer to Gemcitabine Treatment

Cell Proliferation, EarlyView.
ARPC1B+ cancer stem cells (CSCs) in pancreatic cancer are identified as a subpopulation resistant to gemcitabine. In our study, drug repositioning, molecular docking, and surface plasmon resonance (SPR) technique jointly revealed that CK‐636 can directly target ARPC1B protein with high affinity. In vitro cytotoxicity, ex vivo organoid cultures, in vivo
Yang Wu, Jianpeng Zhang, Weixiong Zhu, Xinrui Zhu, Yi Liu, Xin Wang, Tianyu Zhao, Chun Zhang, Zili Zhang, Wenjie Shi, Run Shi, Zhaokai Zhou, Shaohui Xu   +12 more
wiley   +1 more source

From cytogenetics to proteogenomics: new horizons in the study of aneuploidies. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Zadesenets KS, Rubtsov NB.
europepmc   +1 more source

Objective aneuploidy detection for fetal and neonatal screening using comparative genomic hybridization (CGH) [PDF]

, 1997
Loh-Chung Yu, Dan H. Moore, Gregg Magrane, Jack Cronin, Daniel Pinkel, Roger V. Lebo, Joe W. Gray   +6 more
openalex   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Genome-Wide Cell-Free DNA Analysis for Aneuploidy Detection in Miscarriages: Test Performance Meta-Analysis. [PDF]

Prenat Diagn
Pauta M, Martinez-Portilla RJ, Jara-Ettinger AC, Ardiles-Ruesjas V, Borrell A.   +4 more
europepmc   +1 more source

17?-Estradiol, diethylstilbestrol, tamoxifen, toremifene and ICI 164,384 induce morphological transformation and aneuploidy in cultured Syrian hamster embryo cells [PDF]

, 1997
Takeki Tsutsui, Susumu Taguchi, Yuriko Tanaka, J. Carl Barrett   +3 more
openalex   +1 more source

A patient‐derived orthotopic xenograft model unveils metastatic dynamics in head and neck squamous cell carcinoma

The FEBS Journal, EarlyView.
Metastasis in head and neck squamous cell carcinoma (HNSC) poses significant clinical challenges. This proof‐of‐concept study establishes patient‐derived orthotopic xenografts (PDOXs) as advanced models that closely replicate primary HNSC tumours, including local lymph node metastasis and the intricate cancer–stroma interaction.
Yuchen Bai, Benjamin Blyth, Jarryd Boath, Qiji Deng, Ruihong Huang, Charbel Darido   +5 more
wiley   +1 more source

Aneuploidy generates enhanced nucleotide dependency and sensitivity to metabolic perturbation. [PDF]

Genes Dev
Magesh RY, Kaur AN, Keller FN, Frederick A, Tseyang T, Haley JA, Rivera-Nieves AM, Liang AC, Guertin DA, Spinelli JB, Elledge SJ, Watson EV.   +11 more
europepmc   +1 more source

Flow cytometric and clinicopathologic study of 197 hydatidiform moles with special reference to the significance of cytometric aneuploidy and literature review [PDF]

, 1995
Masaharu Fukunaga, Yasuhiko Endo, Shinichiro Ushigome   +2 more
openalex   +1 more source