Response Prediction of Chemoradiotherapy for Rectal Cancer Using Rapid Semi-Automated Flow Cytometry. [PDF]
Amagai H +16 more
europepmc +1 more source
Molecular profile of atypical Leydig cell tumours
Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry +6 more
wiley +1 more source
Copy number variants in fetuses with isolated and non-isolated increased nuchal translucency detected by chromosomal microarray analysis. [PDF]
Huang S, Wu H, She L, Liu L.
europepmc +1 more source
Current Nationwide Landscape of Cardiac Surgery for Children With Trisomy 18 in Japan
ABSTRACT Despite the increasing number of retrospective cohorts describing successful cardiac surgery for children with trisomy 18, no consensus has been reached among healthcare providers regarding cardiac surgery in Japan. This study provided a benchmark to facilitate consensus building by assessing a nationwide surgical database in Japan. A total of
Shintaro Nemoto +5 more
wiley +1 more source
Preimplantation genetic testing for aneuploidy in young women with recurrent spontaneous abortion. [PDF]
Pan Z +5 more
europepmc +1 more source
Flow Cytometry: Advances, Challenges and Trends
Recent advances in flow cytometry span hardware, data processing, and AI‐driven analytics. Emerging modalitiesincluding spectral, imaging, mass, and nano/EV cytometryenable higher‐parameter and small‐particle detection. Integrated machine learning drives a shift from manual gating toward automated multi‐omics workflows.
J. Paul Robinson +2 more
wiley +1 more source
Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models. [PDF]
Hu K +5 more
europepmc +1 more source
586: Pregnancy-associated plasma protein-A (PAPP-A) gene polymorphism and first trimester risk assessment for aneuploidy [PDF]
Shari E. Gelber +4 more
openalex +1 more source
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source
ABSTRACT Objectives MET aberrations are capable of triggering oncogenesis through multiple clinical significance genomic alterations. In non‐small cell lung cancer, MET exon 14 skipping and MET amplification confer sensitivity to MET tyrosine kinase inhibitors. The MET gene is also one of the druggable genes in high‐grade gliomas. However, a systematic
Yu Zhang +5 more
wiley +1 more source

