Results 251 to 260 of about 93,321 (331)

Detection of aneuploidy in chromosomes X, Y, 13, 18 and 21 by QF-PCR in 662 selected pregnancies at risk [PDF]

, 2000
Willi Schmidt
openalex   +1 more source

Euploidy rate and pregnancy outcomes in preimplantation genetic testing for aneuploidy cycles using progestin-primed ovarian stimulation versus GnRH antagonist protocol. [PDF]

Reprod Biol Endocrinol
Tan H, Huang L, Liu W, Yan J, Li L, Wang Y, Huang Y, Xiao Z, Liu F, Zhang X.   +9 more
europepmc   +1 more source

Pediatric predictive testing to inform preimplantation genetic testing: A case report and review of the literature

Journal of Genetic Counseling, Volume 34, Issue 3, June 2025.
Abstract Clinical genetic testing is rapidly expanding in reproductive, pediatric, and adult specialties. We report the case of a couple's request for pediatric genetic testing for a familial Lynch syndrome pathogenic variant, with the goal of utilizing this information to perform preimplantation genetic testing (PGT) on cryopreserved embryos.
Kendra L. Schaa, Renata Thoeny, Rebecca J. Benson, Graeme J. Pitcher, Shelby Romoser, Alpa Sidhu   +5 more
wiley   +1 more source

A Strategy Potentially Suitable for Combined Preimplantation Genetic Testing of Aneuploidy and Monogenic Disease That Permits Direct Detection of Pathogenic Variants Including Repeat Expansions and Gene Deletions. [PDF]

Int J Mol Sci
Tan VJ, Liang Y, Tan AS, Wong S, Asherah N, Chua P, Lee CG, Choolani MA, Dang T, Chong SS.   +9 more
europepmc   +1 more source

Cell Death and Senescence‐Based Molecular Classification and an Individualized Prediction Model for Lung Adenocarcinoma

MedComm, Volume 6, Issue 6, June 2025.
The study systematically investigated 21 cell death and cellular senescence (CDS) features in lung adenocarcinoma, including their expressions, interactions, and immuno‐oncology profiles. Three CDS subtypes were identified to generate a CDS index (CDSI) for personalized regulation patterns.
Pan Wang, Chaoqi Zhang, Peng Wu, Zhihong Zhao, Nan Sun, Qi Xue, Shugeng Gao, Jie He   +7 more
wiley   +1 more source

Activation of Adenosine Phosphate Signaling Promotes Antitumor Immunity in Tumor Microenvironment and Facilitate Immunotherapy

MedComm – Oncology, Volume 4, Issue 2, June 2025.
A comprehensive analysis of the purinergic signaling mediated by P2 receptors (P2Rs) was conducted at both bulk, single‐cell, and spatial transcriptomic levels, evaluating the prognostic and predictive value of the adenosine signaling pathway in cancer immunotherapy.
Yantao Xu, Ying Wang, Zixi Jiang, Yi He, Guowei Zhou, Benliang Wei, Jiachen Liu, Xiang Chen   +7 more
wiley   +1 more source

Implementation of circulating cell-free DNA screening for fetal aneuploidies. [PDF]

Adv Lab Med
Madrigal Bajo I, Jodar Bifet M, Badenas Orquin C.   +2 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

MicroRNA‐371–373 cluster and methylome analysis suggests that a subset of ‘somatic‐type’ malignancies arising in germ cell tumors may originate in yolk sac tumor components

The Journal of Pathology, Volume 266, Issue 2, Page 160-176, June 2025.
Abstract Somatic‐type malignancies (SMs) arising in germ cell tumors (GCTs) are aggressive neoplasms resistant to systemic treatment. Most are diagnosed in metastatic sites after chemotherapy; however, they have also been well‐documented in primary testicular GCTs.
João Lobo, Nuno Tiago Tavares, Diana Fonseca, Carmen Jerónimo, Rui Henrique, Nicolas Wyvekens, Yiying Yang, Matija Snuderl, Fiona Maclean, Jennifer Gordetsky, Christopher DM Fletcher, Michelle S Hirsch, Jason L Hornick, Muhammad T Idrees, Katrina Collins, Laura Warmke, Thomas M Ulbright, Andres M Acosta   +17 more
wiley   +1 more source

Detection of Different Patterns of Genome-Wide Gene Expression Disturbance in Three Nullisomy Lines in Allotetraploid <i>Brassica napus</i>. [PDF]

Plants (Basel)
Lei S, Wei B, Hu Q, Liu L, Yu F, Zeng T, Du X, Gu L, Wang H.   +8 more
europepmc   +1 more source