Results 281 to 290 of about 95,739 (341)

Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation

Advanced Science, Volume 12, Issue 33, September 4, 2025.
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu, Zhuang Wei, Shuting Zhou, Xiaofan Zhang, Wenjun Zhang, Aibin Liang, Zhe Wang, Hongwei Xue   +7 more
wiley   +1 more source

Preimplantation Testing of Human Blastomeres for Aneuploidy Increases IVF Success in Couples Where Male Partners Had Abnormal Semen Parameters. [PDF]

Biomedicines
Ismayilova M, Hasanova A, Semikhodskii A.   +2 more
europepmc   +1 more source

Risk Assessment and Fertility Counseling for Hereditary Gynecological Cancer Syndromes

Cancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Objective To review the genetic basis, clinical characteristics, and management strategies of hereditary gynecologic cancers associated with hereditary cancer syndromes. Methods Literature on germline mutations, inheritance patterns, clinical manifestations, and fertility preservation strategies was reviewed.
Mei Zhao, Xiao‐ming Teng, Qiang Yan, Fan Hao   +3 more
wiley   +1 more source

Biopsy vs comprehensive embryo/blastocyst analysis: a closer look at embryonic chromosome evaluation. [PDF]

Hum Reprod Open
Xu J, Chen Z, Li M, Sun L.
europepmc   +1 more source

A Longitudinal Case Study of Renal Cyst Progression and Regression in Trisomy 13

Clinical Case Reports, Volume 13, Issue 9, September 2025.
Multiple T2‐weighted high‐signal‐intensity structures were observed in both kidneys accompanied by bilateral renal enlargement in a male neonate with trisomy 13. ABSTRACT Trisomy 13 is a chromosomal disorder frequently associated with congenital anomalies, including polycystic kidney disease (PKD).
Fumiko Yamabe, Takahiro Shindo, Kentaro Haneda, Yoshiyuki Namai, Yutaka Harita   +4 more
wiley   +1 more source

Pervasive Chromosomal Instability Drives the Karyotypic Evolution of Hypodiploid Tumours

Loughran E, McLysaght A, Ní Leathlobhair M.   +2 more
europepmc   +1 more source

Dissecting cross‐lineage tumourigenesis under p53 inactivation through single‐cell multi‐omics and spatial transcriptomics

Clinical and Translational Medicine, Volume 15, Issue 9, September 2025.
Construction of a Trp53 functional cell landscape utilising single‐cell multi‐omics and spatial omics technologies. Reconstruction of p53 downstream regulatory relationships with lineage heterogeneity via machine learning‐based gene network modelling.
Xinru Wang, Yuqing Mei, Xueyi Wang, Hanyu Wu, Renying Wang, Peijing Zhang, Guodong Zhang, Jiaqi Li, Mengmeng Jiang, Xing Fang, Lifeng Ma, Yuan Liao, Danmei Jia, Haofu Niu, E Weigao, Haide Chen, Lei Yang, Shuang Zhang, Tingyue Zhang, Yincong Zhou, Qi Zhang, He Huang, Hongwei Ouyang, Ming Chen, Tingbo Liang, Jinrong Peng, Jingjing Wang, Guoji Guo, Xiaoping Han   +28 more
wiley   +1 more source

The Overexpression of Collagen Receptor DDR1 is Associated With Chromosome Instability and Aneuploidy in Diffuse Large B-Cell Lymphoma. [PDF]

J Cell Mol Med
Margielewska-Davies S, Pugh M, Nagy E, Leahy CI, Ibrahim M, Fennell E, Ross A, Bouchal J, Lupino L, Care M, Tooze R, Reynolds G, Rudzki Z, Wei W, Simmons W, Rand V, Hunter K, Reynolds JJ, Stewart GS, Bouchalova K, Douglas IJ, Vrzalikova K, Murray PG.   +22 more
europepmc   +1 more source

Programmed Cell Death in Cancer

MedComm, Volume 6, Issue 9, September 2025.
Cancer is one of the most common and lethal diseases globally, with programmed cell death (PCD) playing a pivotal role in its pathogenesis and treatment. This comprehensive review covers the origin, developmental trajectory, and mechanisms of various PCDs, as well as their molecular connections with cancers. Latest studies have increasingly highlighted
Yuang Wei, William Hankey, Dongliang Xu, Fuwen Yuan   +3 more
wiley   +1 more source

Pre- and Postoperative Cell-Free Fetal DNA Analyses for Detecting Aneuploidy in Early Pregnancy Loss: Single-Center Prospective Cohort Study. [PDF]

Genes (Basel)
Nagao T, Ito Y, Moriyama A, Tei C, Okamoto A, Samura O.   +5 more
europepmc   +1 more source