Results 301 to 310 of about 79,940 (323)
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Aneuploidy in mammalian oocytes and the impact of maternal ageing

Nature reviews. Molecular cell biology, 2022
Chloe Charalambous   +2 more
semanticscholar   +1 more source

Antenatal screening for aneuploidy

Current Opinion in Obstetrics and Gynaecology, 1998
There are several methods of antenatal screening for aneuploidy. Most are aimed at the identification of women at increased risk of Down syndrome, the most common abnormal karyotype conferring a significant risk of serious long-term morbidity. Traditional maternal-age-based screening has largely been replaced by programmes based on biochemical markers ...
openaire   +3 more sources

Aneuploidy and tumorigenesis in Drosophila

Seminars in Cell & Developmental Biology, 2014
Aneuploidy, described as an abnormal number of whole chromosomes or parts of them, has been observed in the majority of sporadic carcinomas, the most common type of cancer occurring in humans and derived from putative epithelial cells. However, the causal relationship between aneuploidy and tumorigenesis remains highly debated.
Milán, Marco   +3 more
openaire   +3 more sources

Effects of aneuploidy on cell behaviour and function

Nature reviews. Molecular cell biology, 2022
Rong Li, Jin Zhu
semanticscholar   +1 more source

Aneuploidy as a promoter and suppressor of malignant growth

Nature Reviews. Cancer, 2021
A. Vasudevan   +5 more
semanticscholar   +1 more source

Tumor aneuploidy predicts survival following immunotherapy across multiple cancers

Nature Genetics, 2022
Liam F. Spurr   +2 more
semanticscholar   +1 more source

Aneuploidy in the Balance

Science, 2007
An extra chromosome slows yeast cell proliferation, suggesting that aneuploid human cells must overcome this effect during carcinogenesis.
David Pellman, Prasad V. Jallepalli
openaire   +2 more sources

The Origin of Aneuploidy in Humans [PDF]

open access: possible, 1985
Aneuploidy is the most common class of chromosome abnormality in humans and is considered by some to be the most important genetic hazard facing man (2). No less than 0.3% of all newborns are aneuploid (12), most with significant physical, intellectual, and behavioral abnormalities. Furthermore, these individuals are the least affected of all aneuploid
openaire   +2 more sources

Sex chromosome aneuploidies

2018
Sex chromosome aneuploidies comprise a relatively common group of chromosome disorders characterized by the loss or gain of one or more sex chromosomes. We discuss five of the better-known sex aneuploidies: Turner syndrome (XO), Klinefelter syndrome (XXY), trisomy X (XXX), XYY, and XXYY.
David Skuse   +2 more
openaire   +3 more sources

Context is everything: aneuploidy in cancer

Nature reviews genetics, 2019
U. Ben-David, A. Amon
semanticscholar   +1 more source

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