Results 41 to 50 of about 7,478 (224)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Wall Orientation and Shear Stress in the Lattice Boltzmann Model

, 2012
The wall shear stress is a quantity of profound importance for clinical diagnosis of artery diseases. The lattice Boltzmann is an easily parallelizable numerical method of solving the flow problems, but it suffers from errors of the velocity field near ...
Aidun, Anor, Artoli, Axner, Berger, Bernsdorf, Bonert, Boussel, Bouzidi, Boyd, Carallo, Caro, Cebral, Cecchi, Chopard, Christ, Cosgrove, Dai, d’Humieres, Gohil, Harvey, He, He, Higuera, Jou, Krüger, Krüger, Ku, Ku, Luo, Maciej Matyka, Malek, McNamara, Meyerson, Milner, Nesbitt, Nickolls, Pantos, Papaioannou, Paszkowiak, Patankar, Peng, Peters, Pohl, Pontrelli, Quarteroni, Reneman, Shaaban, Stahl, Tse, Tölke, Xian, Zbigniew Koza, Łukasz Mirosław   +53 more
core   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Vascular Abnormalities in Hypermobile Ehlers–Danlos Syndrome: A Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypermobile Ehlers–Danlos syndrome (hEDS), while generally free from severe vascular complications, may occasionally present with cardiac and vascular abnormalities that warrant specific investigation. While studies have been conducted on the prevalence of cardiac involvement, none have focused on vascular aspects. This retrospective study was
Thomas Gehin, Malika Foy, Robert Carlier, Valentin Renault, Karelle Benistan   +4 more
wiley   +1 more source

Multiple fusiform aneurysms of the distal middle cerebral artery showing different radiological courses: A case report

Interdisciplinary Neurosurgery, 2017
Middle cerebral artery (MCA) fusiform aneurysms may occur in the proximal MCA, and distal MCA fusiform aneurysms are rare. Here we present a rare case of subarachnoid hemorrhage (SAH) with multiple fusiform aneurysms in the M3 portion, which showed ...
Masatoshi Takagaki, Yuki Togami, Akira Murasawa, Kazutami Nakao   +3 more
doaj   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Genetic Variants in FBN-1 and Risk for Thoracic Aortic Aneurysm and Dissection. [PDF]

, 2014
OBJECTIVES: A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1 gene (encoding Fibrillin-1), were associated with thoracic aortic dissection (TAD ...
AC Morrison, C Olsson, Carmen H. Tong, Charles M. Rowland, D Detaint, DC Guo, Demitrios Nikas, DM Milewicz, DM Milewicz, Gyorgy Ascady, HK Song, JA Elefteriades, JA Elefteriades, John A. Elefteriades, Joseph J. Catanese, JW Olin, L Wang, L Zhu, LA Pape, LJ Goldstein, MA Coady, Maryann Tranquilli, May M. Luke, Olga A. Iakoubova, P Williams, Panagiotis Dedelias, Peter Sotonyi, PM Barrett, Remo M. Moomiaie, S Trimarchi, SA LeMaire, SA LeMaire, Stefan Kiechl, Veronica E. Garcia   +33 more
core   +3 more sources

Unusual rupture of left ventricular pseudo-false aneurysm secondary to subacute anterolateral myocardial infarction: a case report

Journal of Cardiothoracic Surgery, 2019
Background Left ventricular (LV) pseudo-false aneurysm is a rare complication secondary to myocardial infarction and is caused by intramyocardial dissecting hematoma due to fragile myocardium.
Masaho Okada, Hirotaka Watanuki, Kayo Sugiyama, Yasuhiro Futamura, Katsuhiko Matsuyama   +4 more
doaj   +1 more source

Thickening of the pulmonary artery wall in acute intramural hematoma of the ascending aorta [PDF]

, 2007
Background The occurrence of pulmonary artery obstruction in the course of acute aortic dissection is an unusual complication. The mechanism implicated is the rupture of the outer layer of the aorta and the subsequent hemorrhage into the adventitia of ...
Martín Munín, María S Goerner, Martín Lombardero, Gustavo Sanchez, Juan C Pereira Redondo, Fernando Spernanzoni, Héctor Lardani, Víctor Torres, A Evangelista, LM Buja, M Masuo, DF Worsley, AN Rau, S Higashi, C Chiles, E Neri, RJ De Silva   +16 more
core   +2 more sources

King Aorta: Narrative anatomy education

Anatomical Sciences Education, Volume 18, Issue 3, Page 264-276, March 2025.
Abstract The aim of this study was to investigate the effects of narrative anatomy education and traditional anatomy education on academic achievement. The study included 64 students who were randomly divided into two groups. The two groups were (n = 32) control (Group 1) and (n = 32) experimental (Group 2). The pretest scores of the two groups were 36.
Halil Yilmaz
wiley   +1 more source