Results 101 to 110 of about 56,030 (257)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Spontaneous uterine rupture of an unscarred uterus in the second trimester: A case report

International Journal of Gynecology &Obstetrics, EarlyView.
Nour Bakhache, Erica Pascoal, Leah Drost, Alysha Nensi, Michael Ricci, Carmen McCaffrey   +5 more
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Caring for Australians and New ZealandeRs with kidney Impairment guideline commentary on kidney disease: improving global outcomes 2025 guidelines for diagnosis and management of autosomal polycystic kidney disease

Internal Medicine Journal, EarlyView.
Abstract Autosomal polycystic kidney disease (ADPKD) is the most common form of inherited kidney disease. The international guideline developer, Kidney Disease: Improving Global Outcomes (KDIGO), published a 2025 clinical practice guideline reflecting advances in genetic testing and the first disease‐modifying agent, tolvaptan.
Mia E. Abdy, Kitty St Pierre, Emily Major, Stephen I. Alexander, Brydee Cashmore, Helen Coolican, Vanessa Cullen, Jessica Dawson, Kelly Lambert, Vincent W. Lee, Amali Mallawaarachi, Gopala Rangan, Judy Savige, Santosh Varughese, David J. Tunnicliffe, Andrew J. Mallett, on behalf of the CARI Guidelines Steering Committee, Emily See, Leanne Brown, Jonathan Craig, Jeffrey Ha, Rathika Krishnasamy, Casey Light, Emmy O'Neill, Thu Nguyen, Hannah Smith, Andrea Viecelli   +26 more
wiley   +1 more source

Ischemic colitis following infrarenal abdominal aortic aneurysm treatment: Results from a tertiary medical center

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]The aim of this study was to investigate the effects of ruptured aneurysm on morbidity and mortality in patients with ischemic colitis (IC) and resection following infrarenal abdominal aortic aneurysms (AAA) surgery.[¤]METHODS[|]Between ...
Ulas Aday, Ebubekir Gundes, Durmus Ali Cetin, Huseyin Ciyiltepe, Aziz Serkan Senger, Selcuk Gulmez, Mustafa Akbulut, Erdal Polat   +7 more
doaj   +1 more source

Spontaneous thrombosis in a post-traumatic Splenic pseudo-aneurysm. [PDF]

, 2010
Introduction: Splenic pseudo-aneurysm is an uncommon complication following splenic injury caused by blunt abdominal trauma. Pseudo-aneurysm is usually treated with splenic arterial embolisation.
Bux, Shaik Ismail, Mohamad Saini, Suraini   +1 more
core  

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic

Stroke and Vascular Neurology
Background During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study’s objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling ...
, Satoshi Yamada, Thomas G Devlin, David S Liebeskind, Michael D Hill, Tudor G Jovin, Jordi Blasco, Raul G Nogueira, John Thornton, Romain Bourcier, Robert Fahed, Michel Piotin, Salvatore Mangiafico, Maxim Mokin, Shadi Yaghi, Diogo C Haussen, Eytan Raz, Italo Linfante, Vitor Mendes Pereira, Monika Killer-Oberpfalzer, Alhamza R Al-Bayati, Patrick Nicholson, Georgios Tsivgoulis, Vanessa Chalumeau, Lissa Peeling, Xianjin Shang, Hao Zhang, Ajit S Puri, Osama O Zaidat, Santiago Ortega-Gutierrez, Dheeraj Gandhi, Gregory Walker, Kenichi Todo, Ameer E Hassan, Michael Chen, Nobuyuki Sakai, William J Mack, Simon Nagel, Pascal Jabbour, Michael Kelly, Don Frei, Hong Gee Roh, Fawaz Al-Mufti, Emma Griffin, Thanh N Nguyen, Alicia C Castonguay, Roberta Novakovic, Mohamad Abdalkader, Mario Martínez-Galdámez, Toshiyuki Fujinaka, Ken Wong, Daisuke Watanabe, Rishi Gupta, Sunil A Sheth, Melanie Walker, Hiroshi Yamagami, Brendan Steinfort, Alex Brehm, Johanna T Fifi, Nobuyuki Ohara, Yuichi Murayama, Ajay K Wakhloo, Wenguo Huang, Gianmarco Bernava, Paolo Machi, Nabeel Herial, Teddy Y Wu, Anna Luisa Kühn, Markus Möhlenbruch, James E Siegler, Stephan A Mayer, Takuya Kanamaru, André Beer-Furlan, Dileep Yavagal, Charles Matouk, Yuji Matsumaru, Pedro Lylyk, Allan Taylor, Leonardo Renieri, Pablo M Lavados, Verónica V Olavarría, Malveeka Sharma, Marios Psychogios, Laura Mechtouff, Vasu Saini, Jun Luo, Barbara Voetsch, Mudassir Farooqui, Ossama Y Mansour, Viktor Szeder, Jean Raymond, Muhammad M Qureshi, Michael Frankel, Zhongming Qiu, Omer F Eker, Fabricio Oliveira Lima, Francisco Mont'Alverne, Wazim Izzath, Mahmoud Mohammaden, David Ozretic, Saima Ahmad, Umair Rashid, Syed Irteza Hussain, Seby John, Jose Antonio Fiorot, Rodrigo Rivera, Nadia Hammami, Anna M Cervantes-Arslanian, Hormuzdiyar H Dasenbrock, Huynh Le Vu, Viet Quy Nguyen, Steven Hetts, Romain Guile, Atilla Ozcan Ozdemir, Ozlem Aykac, Chandril Chugh, Pascale Lavoie, Randall Edgell, Vikram Huded, Dong Hun Shin, Pedro SC Magalhaes, Raghid Kikano, Amal Abou-Hamden, Tatsuo Amano, Ryoo Yamamoto, Adrienne Weeks, Elena A Cora, Rotem Sivan-Hoffmann, Roberto Crosa, Hosam Al-Jehani, Victor S Lopez Rivera, Achmad Fidaus Sani, Daniel G Abud, Octavio M Pontes-Neto, Brijesh P Mehta, Naoto Kimura, Mamoru Murakami, Jin Soo Lee, Ji Man Hong, Eiji Hagashi, Steve M Cordina, Juan F Arenillas, Alejandro Rodriguez Vasquez, Luisa Fonseca, M Luis Silva, Simon John, Matthew Tenser, Tatemi Todaka, Miki Fujimura, Jun Deguchi, Yuri Sugiura, Hiroshi Tokimura, Rakesh Khatri, Hugh Stephen Winters, Johnny Wong, Mohamed Teleb, Jeremy Payne, Hiroki Fukuda, Kosuke Miyake, Junsuke Shimbo, Yusuke Sugimura, Masaaki Uno, Yohei Takenobu, Ryuhei Kono, Masafumi Morimoto, Junichi Iida, Saif Bushnaq, Jawad Kirmani, Ruchir Shah, Lee Birnbaum, Anchalee Churojana, Hesham E Masoud, Carlos Ynigo Lopez, Alice Ma, Amal Al Hashmi, Mollie McDermott, Alex Chebl, Odysseas Kargiotis, Jane G Morris, Clifford J Eskey, Jesse Thon, Leticia Rebello, Dorothea Altschul, Oriana Cornett, Varsha Singh, Jeyaraj Pandian, Anirudh Kulkarni, Yuki Yamamoto, Gisele Sampaio Silva, Serdar Geyik, Jasmine Johann, Sumeet Multani, Artem Kaliaev, Kazutaka Sonoda, Hiroyuki Hashimoto, Adel Alhazzani, David Y Chung, Zhengzhou Yuan   +197 more
doaj   +1 more source