Results 121 to 130 of about 261,967 (310)
International Journal of Cancer, EarlyView.ABSTRACT Aspirin has been used to treat pain and fever for 120 years. Its uses expanded into treating arthritis and prevention of thrombotic events. Its anti‐cancer role emerged with observational studies in the 1980's and subsequent cancer review in those treated with aspirin in cardiovascular trials.
John Burn, D. Timothy Bishop
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley +1 more source
iNew Medicine, EarlyView.Structural cells (endothelial, epithelial, neural, and muscle) actively participate in innate immunity as primary responders, challenging the traditional leukocyte‐centric paradigm and opening new therapeutic avenues for precision medicine. ABSTRACT Innate immunity has long been viewed as the domain of circulating mobile immune cells orchestrating ...
Sofya Urvanova, Suowen Xu
wiley +1 more source
Coiled Aneurysm with IC Occlusion - SP32-20061216 - 003
, 2006 Imaging of coiled aneurysm with IC ...
Neil R. Miller, MD
core
Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention
ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou +5 more
wiley +1 more source
KLF15 as a Metabolic Gatekeeper Linking Drug Metabolism, Toxicity, and Precision Therapeutics
iNew Medicine, EarlyView.KLF15‐mediated metabolic preconditioning links metabolic state to drug disposition, therapeutic efficacy, and adverse effects, extending classical xenobiotic sensing toward precision pharmacology. ABSTRACT Krüppel‐like factor 15 (KLF15) is emerging as a metabolic‐state‐sensitive regulator of hepatic endobiotic and xenobiotic metabolism.
Shilin Li +3 more
wiley +1 more source
Coiled Aneurysm with ICA Occlusion - SP32-20061216 - 07
, 2006 Imaging of coiled aneurysm with ICA ...
Neil R. Miller, MD
core
Interdisciplinary Medicine, EarlyView.Schematic depicting a gut‐brain pathway that exacerbates CST injury after ICH. Gut Microbiota Dysbiosis‐Mediated Gut NLRP3 Inflammasome Activation Exacerbates Corticospinal Tract Injury After Intracerebral Hemorrhage. Abstract Intracerebral hemorrhage (ICH) causes severe neurological deficits largely attributable to corticospinal tract (CST) injury ...
Meiqin Zeng +11 more
wiley +1 more source
Coiled Aneurysm with ICA Occlusion - SP32-20061216 - 04
, 2006 Imaging of coiled aneurysm with ICA ...
Neil R. Miller, MD
core
Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 547-561, March/April 2025.For patients to benefit from abdominal point‐of‐care ultrasound, the ultrasound examinator must be sufficiently trained. In this systematic review, we identified advantages and disadvantages of different training methods and approaches. We conclude that thoughtful integration of the various educational methods is crucial for stakeholders and educators.
Birkir Örn Sveinsson +5 more
wiley +1 more source