Results 161 to 170 of about 171,483 (267)

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

A Hybrid Covered Stent-Coil Strategy for Complex Dual Aneurysms of the Left Anterior Descending Artery. [PDF]

Anatol J Cardiol
Kıvrak A, Ateş AH, Kaya EB, Şahiner ML, Aytemir K.   +4 more
europepmc   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Microsurgical clip ligation of pericallosal, anterior choroidal, and 2 middle cerebral artery aneurysms through simultaneous transsylvian and interhemispheric approaches: illustrative case. [PDF]

J Neurosurg Case Lessons
Motiwala M, Wu EM, Jones ED, Khan NR.
europepmc   +1 more source

Post-EVAR Endoleaks: A Morphovolumetric Approach to Prediction, Surveillance, and Management. [PDF]

J Clin Med
Külahcıoğlu E, Özçelik S, Koçak NC, Çiçekyurt E, Akkaya BB, Aytekin B, İşcan HZ.   +6 more
europepmc   +1 more source

ARTERIOVENOUS ANEURYSMS

Annals of Surgery, 1938
M R, Reid, J, McGuire
openaire   +3 more sources

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Flow-mediated pseudolesion mimicking an intracranial aneurysm secondary to cervical internal carotid artery dissection: illustrative case. [PDF]

J Neurosurg Case Lessons
Zeng F, Wen F, Fu K, Lin W, Mei Q.
europepmc   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source