Results 91 to 100 of about 9,692 (216)

Lost in Translation: Why Biologic Therapies for Intervertebral Disc Degeneration and Low Back Pain Have Not Reached the Clinic (Yet)

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio   +5 more
wiley   +1 more source

Long-term outcomes of primary surgical repair for communicating DeBakey IIIb chronic dissecting aortic aneurysmCentral MessagePerspective

open access: yesJTCVS Open
Objective: This study aimed to evaluate the long-term outcomes of surgical strategies for communicating DeBakey IIIb chronic dissecting aortic aneurysm, considering the optimal primary surgical repair to prevent aortic events. Methods: From 2002 to 2021,
Shuhei Miura, MD   +9 more
doaj   +1 more source

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

open access: yesBrain Pathology, Volume 36, Issue 5, September 2026.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery   +17 more
wiley   +1 more source

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi   +5 more
wiley   +1 more source

Balloon Passage via Microwire Navigation Technology for Severe Stenosis of Middle Cerebral Artery: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
Schematic representation of the balloon passage via microwire navigation technology. ABSTRACT This case presents that balloon passage via microwire navigation technology could be a beneficial option for patients with severe MCA stenosis, with the diameter of the proximal blood vessel in the stenotic segment is < 1.5 mm and there is antegrade blood flow.
Yang Gao   +10 more
wiley   +1 more source

Structural Restoration of an Unruptured Vertebral Artery Dissection Following Autologous Mesenchymal Stem Cell Therapy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Vertebral artery dissection (VAD) is a recognized cause of ischemic stroke, and current management relies on antithrombotic therapy that is not specifically directed at structural repair of the arterial wall. We report a man in his mid‐50s who presented with a sudden, severe right occipital headache after a golf swing and had a history of a ...
Hyungchang Kang   +3 more
wiley   +1 more source

Early‐Onset Delayed Intraparenchymal Hemorrhage Following Flow Diversion: A Case Report Challenging the Windkessel Hypothesis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Intraoperatively, in a patient with a history of macroadenoma, the cavernous segment of the internal carotid artery was injured. CTA revealed a dissecting pseudoaneurysm at the carotid bifurcation. This case illustrates a fulminant form of DIPH occurring within days of FD deployment.
Feyz Ebrahimnia   +6 more
wiley   +1 more source

DISSEKAN AORT ANEVRİZMASINA BAĞLI AKUT RENAL YETMEZLİK

open access: yesTurkish Journal of Nephrology, 2019
Dissecting aneurysm should be thought in differential diagnosis of acute renal failure which developed in the patients with hypertension.
F. TÜRKMEN   +4 more
doaj  

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