Results 31 to 40 of about 13,674 (178)

Aneurysmal subarachnoid hemorrhage in patients taking direct oral anticoagulants: A case series and discussion of management

Interdisciplinary Neurosurgery, 2018
Direct oral anticoagulants are becoming more commonplace for the treatment of nonvalvular atrial fibrillation and deep vein thrombosis. Unfortunately, effective reversal agents are not widely available limiting options for neurosurgical intervention ...
Joseph H. McMordie, MD, Andrew P. Gard, MD, Daniel L. Surdell, MD, William E. Thorell, MD   +3 more
doaj   +1 more source

Oral Lichenoid Lesions in Patients With Dyskeratosis Congenita: A Retrospective Case Series

Oral Diseases, EarlyView.
ABSTRACT Background Dyskeratosis congenita (DKC) is a rare inherited multisystem disorder primarily affecting the mucocutaneous and hematopoietic systems. Classically, it presents with the ectodermal triad of reticulate skin pigmentation, nail dystrophy, and oral leukoplakia.
Yehuda Zadik, Ori Finfter, Tevel Amiel, Amina Massarwa, Refael Cohen, Jawad Abu Tair, Anna Novikov, Polina Stepensky, Irina Zaidman, Ehud Even‐Or   +9 more
wiley   +1 more source

Different cerebrospinal fluid drainage methods and chronic hydrocephalus in patients with aneurysmal subarachnoid hemorrhage

Frontiers in Neurology
BackgroundChronic hydrocephalus represents a common complication following aneurysmal subarachnoid hemorrhage (aSAH); however, the underlying mechanisms driving its pathogenesis remain incompletely understood.
Yang Zhou, Zhimin Liu, Huiqin Yan, Luyao Peng, Linshuang Chen, Wanyun Wu, Wei Luo, Yongkai Huang, Botao Wu   +8 more
doaj   +1 more source

ARC in Critical Ill OLT Recipients: True Prevalence, Risk Factors, and Impact on Early Aggressive PK/PD Target Non‐Attainment of CI Beta‐Lactam Therapy for Posttransplant Gram‐Negative Infections

Transplant Infectious Disease, EarlyView.
Augmented renal clearance (ARC) represents a quite prevalent condition among critical orthotopic liver transplant recipients (23.2%). ARC is associated with different demographics and clinical features and significantly affects the attainment of aggressive beta‐lactams pharmacokinetic/pharmacodynamic targets despite the administration of standard ...
Milo Gatti, Riccardo De Paola, Matteo Rinaldi, Cristiana Laici, Antonio Siniscalchi, Pierluigi Viale, Federico Pea   +6 more
wiley   +1 more source

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz, Eugènia Pujol, Cristian Ramos, Valeria Rizzo, Christophe Morisseau, Cristina Val, Tiziana Ginex, Javier Vázquez, Sandra Codony, Andreea L. Turcu, Belén Pérez, Elena Sáez, Antonio Pineda‐Lucena, Bruce D. Hammock, F. Javier Luque, M. Isabel Loza, José Brea, Santiago Vázquez   +17 more
wiley   +1 more source

Cerebrospinal Fluid Amyloid‐β Biomarkers Predict Future Hemorrhage in Patients with Cerebral Amyloid Angiopathy

Annals of Neurology, Volume 100, Issue 2, Page 391-399, August 2026.
Objective Accurately predicting future hemorrhagic events in patients with cerebral amyloid angiopathy (CAA) remains a major clinical challenge. It is unknown whether cerebrospinal fluid (CSF) biomarkers of amyloid‐beta (Aβ) pathology are associated with increased hemorrhage risk in this population.
Philipp Arndt, Malte Pfister, Valentina Perosa, Hendrik Mattern, Melis Tas, Lara Holzheimer, Johanna Engel, Marc Dörner, Marwa Al‐Dubai, Cornelia Garz, Eya Khadhraoui, Sebastian J. Müller, Patrick Müller, Sven G. Meuth, Katja Neumann, Stefanie Schreiber   +15 more
wiley   +1 more source

Deep learning-based multiclass segmentation in aneurysmal subarachnoid hemorrhage

Frontiers in Neurology
IntroductionRadiological scores used to assess the extent of subarachnoid hemorrhage are limited by intrarater and interrater variability and do not utilize all available information from the imaging. Image segmentation enables precise identification and
Julia Kiewitz, Julia Kiewitz, Orhun Utku Aydin, Adam Hilbert, Marie Gultom, Anouar Nouri, Ahmed A. Khalil, Peter Vajkoczy, Satoru Tanioka, Fujimaro Ishida, Nora F. Dengler, Nora F. Dengler, Nora F. Dengler, Dietmar Frey, Dietmar Frey   +14 more
doaj   +1 more source

Serum AIM2 as a Prognostic Biomarker for Disease Severity and Delirium in Acute Pancreatitis: A Multicenter Prospective Cohort Study

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Objective Absent in melanoma 2 (AIM2) is implicated in inflammation, and delirium is a common complication following acute pancreatitis (AP). We investigated whether serum AIM2 levels are related to severity and delirium after AP. Methods This multicenter prospective cohort study included 349 patients with AP and 100 controls.
Shiyang Dong, Bo Zhang, Yidong Jing, Shaojun Zhang, Zihao Tang, Jianye Wu, Yujun Rao   +6 more
wiley   +1 more source

Copeptin in aneurysmal subarachnoid hemorrhage [PDF]

Critical Care, 2012
Copeptin is a peptide derived from pre-provasospression along with arginine vasospressin. In the setting of aneurysmal subarachnoid hemorrhage (SAH), elevated serum copeptin levels correlate with vasospasm, inpatient mortality, mortality at 1 year, and poor functional outcome at 1 year.
openaire   +2 more sources

Risk factors for cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage

Open Medicine, 2020
Aneurysmal subarachnoid hemorrhage is a type of spontaneous hemorrhagic stroke, which is caused by a ruptured cerebral aneurysm. Cerebral vasospasm (CVS) is the most grievous complication of subarachnoid hemorrhage (SAH).
Opancina Valentina, Lukic Snezana, Jankovic Slobodan, Vojinovic Radisa, Mijailovic Milan   +4 more
doaj   +1 more source