Results 141 to 150 of about 51,850 (315)
The FEBS Journal, EarlyView.The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Management of aortic aneurysms in patients with connective tissue disease
, 2013 Acute dissection and rupture of aortic aneurysms comprise for 1-2% of all deaths in developed countries. Dilation of the aorta is caused by several different mechanisms including inherited disorders of connective tissue.
Carrel, T P +3 more
core
Familial Thoracic Aortic Aneurysms and Dissections
, 2011 Background— Thoracic aortic aneurysms leading to acute aortic dissections are the major diseases that affect the thoracic aorta.
Jiumei Cao +11 more
core +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
The FEBS Journal, EarlyView.ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
The FEBS Journal, EarlyView.Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Egyptian Journal of NeurosurgeryThis case report describes a 29-year-old woman who experienced a spontaneous subarachnoid haemorrhage due to a left middle cerebral artery aneurysm rupture.
Yuval Willem Belisha +3 more
doaj +1 more source
Rare case of inflammatory abdominal aortic aneurysm with an aortocaval fistula
Radiology Case ReportsInflammatory abdominal aortic aneurysms (IAAA) are a distinct subcategory of abdominal aortic aneurysms that make up roughly 5%-10% of all abdominal aortic aneurysm (AAA) cases.
Richard Pham, BA +5 more
doaj +1 more source
Suzetrigine as a novel treatment for headache disorders: A case series
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald +15 more
wiley +1 more source