Results 21 to 30 of about 51,850 (315)

High-intensity interval exercise training before abdominal aortic aneurysm repair (HIT-AAA): protocol for a randomised controlled feasibility trial [PDF]

, 2014
Introduction: In patients with large abdominal aortic aneurysm (AAA), open surgical or endovascular aneurysm repair procedures are often used to minimise the risk of aneurysm-related rupture and death; however, aneurysm repair itself carries a high risk.
Kerr, K., Kerr, Karen, Weston, Matthew; id_orcid, Tew, G.A., Tew, Garry A, Tew, Garry, Danjoux, Gerard, Batterham, A.M., Batterham, Alan M, Alan M Batterham, Gray, Joanne, Martin, D., Danjoux, Gerard R., Nawaz, Shah, Matthew Weston, Yates, David, Weston, M., Elke Kothmann, Tew, G. A. (Garry), Gerard Danjoux, Gray, J., Weston, Matthew, Yates, D., Garry A Tew, Kothmann, Elke, Martin, Denis, Denis Martin, Martin, Denis; id_orcid, Nawaz, S., Batterham, Alan, Shah Nawaz, Kothmann, E., Joanne Gray, Danjoux, G., David Yates, Karen Kerr   +35 more
core   +1 more source

Downregulation of the Yes-Associated Protein Is Associated with Extracellular Matrix Disorders in Ascending Aortic Aneurysms

Stem Cells International, 2016
Previous studies indicate that extracellular matrix (ECM) disorders lead to the apoptosis of Vascular Smooth Muscle Cells (VSMCs), which impairs the aortic wall by reducing the generation of elastic fibers, and ultimately result in ascending aortic ...
Haiyang Li, Wenjian Jiang, Weihong Ren, Dong Guo, Jialong Guo, Xiaolong Wang, Yuyong Liu, Feng Lan, Jie Du, Hongjia Zhang   +9 more
doaj   +1 more source

Spectrum of ascending aortic aneurysms at a peri-urban tertiary hospital: an echocardiography-based study

Frontiers in Cardiovascular Medicine, 2023
IntroductionThoracic ascending aortic (TAA) aneurysms are an important cause of disability and death and require early detection for effective management. Currently, there is a paucity of data from Africa pertaining to TAA aneurysms. This study describes
Ruchika Meel, Michael Hasenkam, Ricardo Goncalves, Kelly Blair, Shungu Mogaladi   +4 more
doaj   +1 more source

Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening [PDF]

, 2012
Background: The long-term effects of abdominal aortic aneurysm (AAA) screening were investigated in extended follow-up from the UK Multicentre Aneurysm Screening Study (MASS) randomized trial.
Gao, L, Thompson, SG, Ashton, HA, Scott, RAP, Buxton, MJ   +4 more
core   +1 more source

MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms. [PDF]

PLoS ONE, 2016
The need for biological markers of aortic wall stress and risk of rupture or dissection of ascending aortic aneurysms is obvious. To date, wall stress cannot be related to a certain biological marker.
Anke Tscheuschler, Philipp Meffert, Friedhelm Beyersdorf, Claudia Heilmann, Nadja Kocher, Xenia Uffelmann, Philipp Discher, Matthias Siepe, Fabian A Kari   +8 more
doaj   +1 more source

Cost-effectiveness of the National Health Service Abdominal Aortic Aneurysm Screening Programme in England. [PDF]

, 2014
BACKGROUND: Implementation of the National Health Service abdominal aortic aneurysm (AAA) screening programme (NAAASP) for men aged 65 years began in England in 2009.
Thompson, SG, Glover, MJ, Kim, LG, Buxton, MJ, Sweeting, MJ   +4 more
core   +1 more source

Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm. [PDF]

, 2013
BACKGROUND: Single-centre series of the management of patients with ruptured abdominal aortic aneurysm (AAA) are usually too small to identify clinical factors that could improve patient outcomes.
Hinchliffe, RJ, Thompson, MM, Bell, R, Greenhalgh, R. M., Ashleigh, R., Grieve, RJ, Ulug, P., Heatley, F., Powell, JT, Sweeting, M. J., Ashleigh, R, Heatley, F, Thompson, S. G., Powell, J. T., Greenhalgh, RM, Gomes, M, Ulug, P, Sweeting, MJ, Gomes, M., ?, ?, Thompson, SG, Hinchliffe, R. J., IMPROVE trial investigators, Thompson, M. M., Bell, Rachel, Grieve, R. J.   +25 more
core   +1 more source

The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. [PDF]

, 2015
Introduction Chronic thoracic aortic aneurysm (CTAA) affecting the arch or descending aorta is an indolent but life-threatening condition with a rising prevalence as the UK population ages.
Catarino, P., ETTAA Collaborators, Gray, J, Vallabhaneni, S, Vale, L., Vallabhaneni, Srinivasa, Cook, A., Moorjani, N, Moorjani, Narain, Vale, Luke, Sharples, L., Gray, Joanne, Cook, Andrew, Elefteriades, JA, Sastry, P., Sharples, Linda, Vallabhaneni, S. R., Sastry, P, Moorjani, N., Hughes, V., Elefteriades, John, Cook, A, Catarino, Pedro, Hughes, V, Elefteriades, J., Hayes, P, on behalf of the ETTAA collaborators, Thompson, M., Hayes, P., Gray, J., Vale, L, Large, Stephen, Catarino, P, Thompson, Matt, Sharples, L, Hughes, Victoria, Elefteriades, John A, Hayes, Paul, Thompson, M, Sastry, Priya, Large, Stephen R, Large, SR, Large, S. R.   +42 more
core   +1 more source

Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication

Redox Biology, 2022
Aortic aneurysms are prevalent and severe vascular diseases with high mortality from unpredicted ruptures, while the only treatment option is surgical correction of large aneurysms with considerable risk.
Kai Huang, Yusi Wu, Yixuan Zhang, Ji Youn Youn, Hua Cai   +4 more
doaj   +1 more source

Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level

Frontiers in Pharmacology, 2023
Introduction: Aortic aneurysm is a life-threatening disease resulted from progressive dilatation of the aorta, which can be subdivided into thoracic and abdominal aortic aneurysms.
Hong Wu, Cheng Xie, Ruilin Wang, Jun Cheng, Qingbo Xu, Haige Zhao   +5 more
doaj   +1 more source