Results 51 to 60 of about 51,850 (315)

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Elective Open Suprarenal Aneurysm Repair in England from 2000 to 2010 an Observational Study of Hospital Episode Statistics

, 2013
Background: Open surgery is widely used as a benchmark for the results of fenestrated endovascular repair of complex abdominal aortic aneurysms (AAA).
Hinchliffe, RJ, Jan D Poloniecki, Thompson, MM, Holt Peter J. E., Sollazzo Giuseppe, Hinchliffe Robert J., Alan Karthikesalingam, Robert J Hinchliffe, Matthew M Thompson, Peter J E Holt, Poloniecki, JD, Karthikesalingam, A, Patterson Benjamin O., Thompson Matthew M., Benjamin O Patterson, Giuseppe Sollazzo, Holt, PJ, Vidal-Diez, A, Sollazzo, G, Vidal-Diez Alberto, Karthikesalingam Alan, Patterson, BO, Alberto Vidal-Diez, Poloniecki Jan D.   +23 more
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Placement of an aortomonoiliac stent graft without femorofemoral revascularization in endovascular aneurysm repair: a case report

, 2011
Introduction: Endovascular aortic repair, if technically feasible, is the treatment of choice for patients with a contained ruptured aortic aneurysm who are unfit for open surgery. Case presentation: We report the case of an 80-year-old Caucasian man who
Diehl, Steffen Johannes, Schoenberg Stefan, Keese Michael, Keese, Michael, Diehl Steffen, Niedergethmann, Marco, Schönberg, Stefan, Michael Keese, Steffen Diehl, Stefan Schoenberg, Niedergethmann Marco, Marco Niedergethmann   +11 more
core   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

A Markov decision analysis model to aid the vascular surgeon in the management of a patient with an asymptomatic infra-renal abdominal aortic aneurysm [PDF]

, 2010
Introduction Despite increasing evidence regarding the safety and efficacy of endovascular (EVAR) and open abdominal aortic aneurysm repair, it is often unclear which technique is most appropriate for an individual patient.
Drury, Duncan
core  

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Vascular Abnormalities in Hypermobile Ehlers–Danlos Syndrome: A Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypermobile Ehlers–Danlos syndrome (hEDS), while generally free from severe vascular complications, may occasionally present with cardiac and vascular abnormalities that warrant specific investigation. While studies have been conducted on the prevalence of cardiac involvement, none have focused on vascular aspects. This retrospective study was
Thomas Gehin, Malika Foy, Robert Carlier, Valentin Renault, Karelle Benistan   +4 more
wiley   +1 more source

Biomechanics of Aortic Dissection: A Comparison of Aortas Associated With Bicuspid and Tricuspid Aortic Valves

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Current methods for aortic dissection risk assessment are inadequate for patients with ascending aortic aneurysms associated with either bicuspid aortic valves (BAVs) or tricuspid aortic valves (TAVs).
Jennifer C.‐Y. Chung, Edwin Wong, Mingyi Tang, Daniella Eliathamby, Thomas L. Forbes, Jagdish Butany, Craig A. Simmons, Maral Ouzounian   +7 more
doaj   +1 more source

Artificial intelligence in the diagnosis of thoracic aortic aneurysms in a retrospective chest computed tomography scan analysis

Digital Diagnostics, 2023
BACKGROUND: Aortic aneurysms, known as silent killers, are frequently asymptomatic, leading to vessel rupture and death. Annual rates for ruptures, stratifications, and sudden deaths are up to 3.6%, 3.7%, and 10.8%, respectively.
Alexander V. Solovev, Valentin E. Sinitsyn, Alexey V. Petraikin, Anton A. Vladzymyrskyy, Roman V. Reshetnikov   +4 more
doaj   +1 more source