Results 151 to 160 of about 106,477 (267)

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Clinical Utility of a Feedback Device in High-Quality Cardiopulmonary Resuscitation: The Guardian Angel. [PDF]

J Clin Med
Fernández-Sarmiento J, Sanmiguel-Benavides AR, Contreras JP, Bastidas A, Trujillo JC, Uribe J, Botero-Rosas D, Tuta-Quintero E.   +7 more
europepmc   +1 more source

Understanding the Aqueous Self‐Assembly of Raw Sophorolipid Mixtures Using a Statistical Approach Applied to Synchrotron Small Angle X‐Ray Scattering (SAXS): A Focus on pH, Dilution, Aging, and the Underestimated Role of Residual Fatty Acids

Journal of the American Oil Chemists' Society, EarlyView.
The statistical analysis of SAXS modelling data allows to identify the critical physicochemical parameters that have an impact on the phase behavior of crude sophorolipid batches. ABSTRACT The aqueous self‐assembly of raw sophorolipid mixtures has been studied by small angle x‐ray scattering (SAXS) to understand the impact of the composition ...
Maia Ouret‐Campagnet, Sélène Chappuis, Jean‐Christophe Castaing, Petra Pernot, François Ribot, Niki Baccile   +5 more
wiley   +1 more source

The Americas are not on track to end TB: tuberculosis incidence analysis under the 2025 WHO goals. [PDF]

Front Public Health
Rodríguez-Pazmiño ÁS, Orlando SA, Cardenas Franco C, Carvajal E, Paredes DS, Franco Sotomayor G, Garcia-Bereguian MA.   +6 more
europepmc   +1 more source

Changing a Winning Team—Replacement of Brominated Flame Retardant and Antimony Trioxide in Acrylonitrile–Butadiene–Styrene

Journal of Applied Polymer Science, EarlyView.
This comprehensive study investigates reducing the amount of brominated flame retardant (Br) and/or antimony trioxide (ATO) in acrylonitrile–butadiene–styrene. Therefore, condensed‐phase flame‐retardant mechanisms are introduced into the flame‐inhibition system.
Sebastian M. Goller, Bernhard Schartel, Simone Krüger   +2 more
wiley   +1 more source

Commissioning in water of HDR Valencia skin applicators. [PDF]

Rep Pract Oncol Radiother
Rodríguez LÁQ, Ríos LP, Oquendo MAI.
europepmc   +1 more source

Long‐Time Thermal Aging of Perfluoroalkoxy Polymers for Electrical Insulation: Structural and Physical Properties Evolutions

Journal of Applied Polymer Science, EarlyView.
This work focuses on the investigation of the influence of a long‐time exposition to accelerated thermal aging on the physicochemical structure and properties of PFA. Results show a decrease in the melting temperature and crystal ratio due to chemical aging.
Victor Henri, Julien Chedaille, Pierre Henrard, Eric Dantras   +3 more
wiley   +1 more source

Ultrasound-Guided Pulsed Radiofrequency of the Sciatic Nerve for Chronic Lower Limb Pain: A Real-World Cohort Experience. [PDF]

Cureus
González Godoy E, Cardoso P, De la Rocha Vedia IV, Plasencia Ezaine Á, Arenal López R, Méndez Leo ML, Rojas Sánchez A, Ruiz de Castañeda Zamora MD, Fernández Ordóñez M, Ramírez Huaranga M.   +9 more
europepmc   +1 more source

Expanded application to plant reproductive tissues of a branched DNA probe‐based in situ hybridization method

Applications in Plant Sciences, EarlyView.
Abstract Premise Detecting clear tissue‐ and organ‐specific patterns of gene expression is key to understanding the genetic mechanisms that control plant development. In situ hybridization (ISH) of mRNA is one of the most precise, yet most challenging approaches to gene expression assays.
Brooklyn M. Anaya, Austin T. Nguyen, Kelly K. S. Matsunaga, Lena C. Hileman   +3 more
wiley   +1 more source

First record of <i>Licnophora chattoni</i> (Ciliophora, Spirotrichea) on the sabellid worm <i>Bispira melanostigma</i> from marina fouling communities. [PDF]

Biodivers Data J
de León-González JA, Mayén-Estrada R, Carrera-Parra LF, García Garza ME, Tovar-Hernández MA.   +4 more
europepmc   +1 more source