Results 221 to 230 of about 945,874 (299)

Real‐World Effectiveness of Switching to Oral or Infusion Versus Injectable Disease‐Modifying Therapy in Pediatric Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective To assess real‐world effectiveness of switching disease‐modifying therapy (DMT) in pediatric multiple sclerosis (MS) and clinically isolated syndrome (CIS) initially treated with platform injectables on disease activity. Methods Of 2615 pediatric‐onset demyelinating disease patients at 12 clinics in the United States (US) Network of Pediatric
Aaron W. Abrams   +27 more
wiley   +1 more source

Persistent Mono‐Oxo Bonding with Protactinium(V) Revealed in Highly Acidic Chloride Solutions

open access: yesAngewandte Chemie, EarlyView.
Protactinium(V) defies expectations. Its elusive mono‐oxo bond was revealed through a combination of extended X‐ray absorption fine structure (EXAFS) and X‐ray absorption near‐edge structure (XANES) analyses, as well as quantum chemical calculations. This bond persists even in 12 M HCl.
Melody Maloubier   +9 more
wiley   +2 more sources

Correction: Chemical profiling, antioxidant, and antibacterial properties of <i>Tropaeolum majus</i> L. extract as a functional food ingredient. [PDF]

open access: yesFront Nutr
Aguilera-Angel EY   +12 more
europepmc   +1 more source

Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale

open access: yesAnnals of Neurology, EarlyView.
Objective Dopaminergic imaging is a key biomarker for both the investigation of the biology of Parkinson's disease and related synucleinopathies and the evaluation of potential therapies in clinical trials. This work presents a harmonized approach for quantifying dopaminergic molecular imaging tracers, such as [123I]ioflupane (dopamine transporter scan
Zhen Fan   +174 more
wiley   +1 more source

Stereospecific Assembly of Triply Chiral Pseudopeptidic Cages Through Dynamic Dual Chirality Transfer

open access: yesAngewandte Chemie, EarlyView.
The spontaneous assembly of triply chiral (L, Δ, P or D, Λ, M) cages has been achieved from a simple tripodal chiral effector based on phenylalanine tris(amidoamine), non‐chiral bipyridine dialdehyde, and a metal ion. Orthogonal imine bond and iron (II) coordination generate a single combination of chiral elements, while configurationally stable ...
Tushar D. Bhosale   +6 more
wiley   +2 more sources

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

open access: yesAnnals of Neurology, EarlyView.
Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains a significant challenge.
Yue Qiao   +4 more
wiley   +1 more source

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