Results 141 to 150 of about 881,149 (300)

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

open access: yesAngewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe   +7 more
wiley   +1 more source

Polyfluoroalkyl‐Tagged Cell‐Penetrating Peptide‐Additives Enhance Intracellular Protein Delivery via Sustained Monomeric Lipid Interaction

open access: yesAngewandte Chemie International Edition, EarlyView.
We introduce cell‐penetrating peptides (CPPs) with polyfluoroalkyl‐tags that drastically enhance intracellular protein delivery by promoting membrane retention. Via the combination of live‐cell imaging, biophysical analysis, and computational simulations, we reveal how fluorous CPPs interact with membranes via monomeric interactions and dynamic tag ...
Sarah Hansen   +10 more
wiley   +1 more source

Investigation of anger levels in adolescent individuals in terms of educational game variable

open access: yesTürk Spor ve Egzersiz Dergisi, 2016
This study was carried out in order to investigate anger levels of adolescent students between 15 and 16 years old.The sample of the research constituted of 52 students (experiment group) who participated in physical education course and were applied 8 ...
Mehibe Akandere
doaj  

Geminal Difunctionalization of Ketones via C─S Bond Insertion of Photogenerated Donor–Donor Diazo Compounds

open access: yesAngewandte Chemie International Edition, EarlyView.
Geminal difunctionalization of readily available building blocks provides rapid access to molecular complexity. This work introduces a strategy for installing two distinct functional groups on a carbonyl carbon by transforming it into a donor–donor diazo compound, enabling both batch and flow applications with broad solvent compatibility.
Vincent George   +13 more
wiley   +1 more source

Macroeconomic Impacts of the Clean Development Mechanism: The Role of Investment Barriers and Regulations [PDF]

open access: yes
This paper quantifies the macroeconomic impacts of the Clean Development Mechanism (CDM) under the Kyoto Protocol based on a computable general equilibrium (CGE) model of international trade and energy use.
Anger, Niels   +2 more
core  

Design of Experiments‐Based Optimization of Recovered Carbon Black–Reinforced Isobutylene–Isoprene Rubber in Comparison With Conventional Carbon Black Systems

open access: yesJournal of Applied Polymer Science, EarlyView.
Optimized potential of rCB via DOE: recovered carbon black from end‐of‐life tires was assessed as a full substitute for conventional carbon black in IIR composites. DOE and response surface methodology optimized rCB loading, plasticizer, and sulfur contents. Hardness showed linear trends, while rupture energy was nonlinear.
Vinícius Guedes Gobbi   +3 more
wiley   +1 more source

Interactions of Reduced Deforestation and the Carbon Market: The Role of Market Regulations and Future Commitments [PDF]

open access: yes
Reducing emissions from deforestation and degradation (REDD) has been proposed as a potentially inexpensive and plentiful source of emission abatement to supplement other longterm climate policies.
Anger, Niels   +2 more
core  

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

open access: yesAnimal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang   +11 more
wiley   +1 more source

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