Results 111 to 120 of about 396,597 (302)

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke   +14 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright   +8 more
wiley   +1 more source

Psychoeducation Reduces Alexithymia and Modulates Anger Expression in a School Setting. [PDF]

open access: yesChildren (Basel), 2022
Iuso S   +5 more
europepmc   +1 more source

[Review of] Silvester Brito. Red Cedar Warrior [PDF]

open access: yes, 1988
Red Cedar Warrior, the collection of poems by S.J. Brito, is very obvious in its depiction of trepidations against Native Americans, in its mourning for the loss of culture and traditions, and its expression of anger.
Ortiz, Simon J.
core   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

open access: yesAdvanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim   +4 more
wiley   +1 more source

Relationship between Anger Expression in Mothers and Acceptance of Behavior Management Techniques in Pediatric Dentistry. [PDF]

open access: yesJ Dent (Shiraz), 2023
Faghihian R   +4 more
europepmc   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

open access: yesAdvanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng   +5 more
wiley   +1 more source

Examining Research Domain Criteria (RDoC) constructs for anger expression and regulation in toddlers. [PDF]

open access: yesJ Psychopathol Clin Sci, 2022
Liu C   +8 more
europepmc   +1 more source

Silent Struggle: Confronting Anger in African-American Women [PDF]

open access: yes, 2010
In the field of mental health, disorders such as anxiety and depression have been recognized for decades as debilitating ailments that often require professional treatment.
Oprean, Amy
core   +1 more source

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