Results 101 to 110 of about 594,807 (242)

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, EarlyView.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source

Serious Mental Illness‐Associated Socio‐Medical Needs and Imprisonment Risk in Reentry Clients

Psychiatric Research and Clinical Practice, EarlyView.
Objective To examine whether the socio‐medical needs and imprisonment risk among transitional care clients with serious mental illness (SMI) differ from other transitional care clients. Methods A retrospective cohort study was conducted of adults who entered the Formerly Incarcerated Transition (FIT) Program from 2018 to 2023 following a period of ...
David L. Rosen, Theodore R. Zarzar, Anna Baker, Evan A. Ashkin   +3 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

OCT‐Guided Distal Left Main Bifurcation PCI: Mid‐Term Outcomes From a Multicenter South‐Asian Registry

Catheterization and Cardiovascular Interventions, Volume 107, Issue 2, Page 477-484, February 1, 2026.
ABSTRACT Background Optical coherence tomography (OCT)‐guided percutaneous coronary intervention (PCI) enhances treatment of complex coronary artery lesions, including left main (LM) disease, by enabling lesion morphology assessment and stent optimization, thereby reducing major adverse cardiac events (MACE).
Prathap Kumar, Shaneez Najmy, Manu Rajendran, Ali Shafeeq, Blessvin Jino   +4 more
wiley   +1 more source

Patient‐Specific Lumped‐Parameter Model for Quantifying Vessel‐Specific Remodeling and Predicting Right Ventricular Function in Pulmonary Hypertension

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
Personalized, patient‐specific biophysical model enabling mechanistic assessment of right ventricular (RV) function as well as robust differentiation of pulmonary hypertension (PH) subtype from routine clinical measurements of pulmonary arterial pressure and flow.
Christopher G. Lechuga, Amirreza Kachabi, Mitchel J. Colebank, Claudia E. Korcarz, Farhan Raza, Naomi C. Chesler   +5 more
wiley   +1 more source

Computer Vision‐Guided Automated External Defibrillator System Improves Cardiopulmonary Resuscitation Accuracy: A Randomized Crossover Trial

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Out‐of‐hospital cardiac arrests (OHCAs) remain a critical challenge in emergency care, as CPR effectiveness heavily relies on precise chest compressions. We propose a novel CPR guidance system using computer vision to track rescuer motion in real time.
Li Liu, Hua Huang, Pengcheng Zhao, Yan Chen, Sixing Liu, Qun Wu, Wei Jing, Mingjie Yin, Yongyuan Li, Jiahuan Lu, Xicheng Zhang, He Xu, Yimu Ji   +12 more
wiley   +1 more source

Platelets of unstable angina patients as effector cells in terahertz radiation at NO frequency

Кардиоваскулярная терапия и профилактика, 2005
Aim. To investigate the effects of electromagnetic terahertz waves at NO MSIP (molecular specter of radiation and absorption), 240 Hz, on platelet functional activity Р in natural electromagnetic field, as well as in crossed magnetic and electric fields ...
V. F. Kirichuk, E. V. Andronov, A. P. Krenitsky, V. D. Tupikin, A. V. Mayborodin, O. V. Betsky   +5 more
doaj  

Can patients with left main coronary artery disease wait for myocardial revascularization surgery?

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To assess the occurrence of cardiac events in patients diagnosed with left main coronary artery disease on diagnostic cardiac catheterization and waiting for myocardial revascularization surgery.
Antônio Sérgio Cordeiro da Rocha, Paulo Roberto Dutra da Silva   +1 more
doaj   +1 more source

Skeletal Muscle Mass Modifies the Prognostic Impact of LDL Cholesterol in Chronic Heart Failure

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Dyslipidaemia is among the major risk factors for atherosclerotic cardiovascular disease. Paradoxically, higher cholesterol levels are associated with better survival in heart failure (HF) of any aetiology. Because cholesterol is an integral component of skeletal muscle structure, one possible explanation involves the interplay ...
Ryosuke Sato, Tania Garfias‐Veitl, Guglielmo Fibbi, Mirela Vatic, Wolfram Doehner, Stefan D. Anker, Stephan von Haehling   +6 more
wiley   +1 more source