Results 171 to 180 of about 579,295 (296)

Immune cell dynamics in heart failure: implicated mechanisms and therapeutic targets

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 1739-1758, June 2025.
Abstract The relationship between heart failure (HF) and immune activation has garnered significant interest. Studies highlight the critical role of inflammation in HF, affecting cardiac structure and function. Despite promising anti‐inflammatory therapies, clinical trials have faced challenges, indicating an incomplete understanding of immune ...
Gen Li, Wu He, Dao Wen Wang
wiley   +1 more source

Brain Aging in Patients With Cardiovascular Disease From the UK Biobank

open access: yesHuman Brain Mapping, Volume 46, Issue 8, June 1, 2025.
This study reveals that in patients with certain cardiovascular diseases there is atypical biological brain age predicted by an artificial intelligence model from T1‐weighted brain MRIs. This suggests the existence of distinct aging‐like patterns within the brain in the precense of cardiovascular conditions.
Elizabeth Mcavoy   +4 more
wiley   +1 more source

Concomitant Increases in Brain‐Derived Neurotrophic Factor and Lactate Post‐Exercise Do Not Demonstrate a Direct Correlation

open access: yesJournal of Neuroscience Research, Volume 103, Issue 6, June 2025.
While BDNF and lactate concentrations are responsive to a submaximal graded exercise test in a healthy population, lactate cannot be used as an alternative to BDNF and subsequently may not be an indication of BDNF‐associated neuroplasticity. ABSTRACT The aim of this study was to determine the relationship between BDNF and lactate concentration ...
S. K. Ashcroft   +8 more
wiley   +1 more source

A Novel Intravascular Lithotripsy System in Severely Calcified Coronary Lesions: The Prospective COronary CAlcified Lesion Lithotripsy Procedure (COCALP) Study

open access: yesMedComm, Volume 6, Issue 6, June 2025.
Safety and effectiveness of the novel intravascular lithotripsy (IVL) device: The overall success rate of the novel intravascular lithotripsy (IVL) device (A) is 97.4%, with no significant differences observed across subgroups (age, gender, hypertensive, bifurcation, lesion length and lumen narrowing) (B).
Xin Deng   +14 more
wiley   +1 more source

Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma

open access: yesMed Research, Volume 1, Issue 1, Page 122-130, June 2025.
ABSTRACT Primary malignant pericardial mesothelioma (PMPM), a rare pericardium‐derived malignancy, urgently requires standardized diagnostic and therapeutic protocols. This consensus, established by the Chinese Alliance of Research for Mesothelioma (ChARM) through the integration of evidence‐based research and multicenter clinical expertise, addresses ...
Qing Ji   +112 more
wiley   +1 more source

Clarithromycin Versus Azithromycin for Community‐Acquired Pneumonia and the Risk of Major Adverse Cardiovascular Events: A Multicentre Cohort Study Using Data From Canada and Denmark

open access: yesPharmacoepidemiology and Drug Safety, Volume 34, Issue 6, June 2025.
ABSTRACT Background Studies suggest that clarithromycin is associated with an increased risk of major adverse cardiovascular events (MACE) among adults with coronary artery disease. However, data comparing clarithromycin to other macrolides, such as azithromycin, in a broader population are lacking.
Theis Skovsgaard Itenov   +14 more
wiley   +1 more source

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