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Angiography in unstable angina
The American Journal of Cardiology, 1991Within the last decade, it has been appreciated that the acute coronary syndromes of unstable angina, non-Q-wave, and Q-wave myocardial infarction often share a common pathogenesis based on plaque disruption and thrombosis. Such "acute" lesions frequently have a characteristic angiographic appearance with sharp overhanging edges, irregular borders, and
Douglas H. Israel, John A. Ambrose
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New England Journal of Medicine, 1983
We conducted a multicenter, double-blind, placebo-controlled randomized trial of aspirin treatment (324 mg in buffered solution daily) for 12 weeks in 1266 men with unstable angina (625 taking aspirin and 641 placebo). The principal end points were death
H. Lewis+12 more
semanticscholar +1 more source
We conducted a multicenter, double-blind, placebo-controlled randomized trial of aspirin treatment (324 mg in buffered solution daily) for 12 weeks in 1266 men with unstable angina (625 taking aspirin and 641 placebo). The principal end points were death
H. Lewis+12 more
semanticscholar +1 more source
Unstable angina and thrombolysis
Chest, 1990Unstable angina occurs in a heterogeneous population of patients. In the subset of patients with recent rest angina, both angiographic and angioscopic studies have suggested that coronary artery thrombus is often present and serves as a predictor of subsequent adverse clinical events, including recurrent angina, myocardial infarction, the need for ...
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New England Journal of Medicine, 1986
The hallmark of unstable angina is its unpredictability. The symptoms, which occur without provocation, sometimes stabilize or resolve but sometimes progress to myocardial infarction or sudden death. This pattern contrasts with that of stable angina.
Valentin Fuster, James H. Chesebro
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The hallmark of unstable angina is its unpredictability. The symptoms, which occur without provocation, sometimes stabilize or resolve but sometimes progress to myocardial infarction or sudden death. This pattern contrasts with that of stable angina.
Valentin Fuster, James H. Chesebro
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Identification of biomarkers for unstable angina by plasma metabolomic profiling.
Molecular Biosystems, 2013Unstable angina (UA) is one of the most dangerous types of coronary heart disease and has high mortality and morbidity rates worldwide. However, the diagnostic accuracy for UA is unsatisfactory in clinical practice.
Meng Sun+9 more
semanticscholar +1 more source
American Heart Journal, 1976
Unstable angina is a syndrome which comprises a spectrum of symptomatic manifestations of coronary artery disease which lies between stable angina pectoris and acute myocardial infarction. Patients fall into three groups: angina of recent onset (4 weeks), angina of changing pattern, and angina occurring at rest (longer than 15 minutes).
Ivan George Fantus+2 more
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Unstable angina is a syndrome which comprises a spectrum of symptomatic manifestations of coronary artery disease which lies between stable angina pectoris and acute myocardial infarction. Patients fall into three groups: angina of recent onset (4 weeks), angina of changing pattern, and angina occurring at rest (longer than 15 minutes).
Ivan George Fantus+2 more
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Hospital Medicine, 2000
Unstable angina is a common condition that presents a challenge to physicians because of its complex pathophysiology, and because of the high incidence of associated death and myocardial infarction. This article summarizes key strategies that can be employed in managing unstable angina and describes their interaction with the mechanisms that underpin ...
Neil R. Grubb, Keith A.A. Fox
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Unstable angina is a common condition that presents a challenge to physicians because of its complex pathophysiology, and because of the high incidence of associated death and myocardial infarction. This article summarizes key strategies that can be employed in managing unstable angina and describes their interaction with the mechanisms that underpin ...
Neil R. Grubb, Keith A.A. Fox
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Aspirin, heparin, or both to treat acute unstable angina.
New England Journal of Medicine, 1988We tested the usefulness of aspirin (325 mg twice daily), heparin (1000 units per hour by intravenous infusion), and a combination of the two in the early management of acute unstable angina pectoris in a double-blind, randomized, placebo-controlled ...
P. Théroux+12 more
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European Heart Journal, 1993
Treatment of both stable and unstable angina depends on initially defining the pathophysiological mechanisms. The goal of treatment is to prevent the development of angina pectoris and possibly also to improve the prognosis. beta-blockade is effective in treating effort-related angina, as are calcium antagonists, which are also effective in treating ...
David Mulcahy, Kim Fox, H. Purcell
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Treatment of both stable and unstable angina depends on initially defining the pathophysiological mechanisms. The goal of treatment is to prevent the development of angina pectoris and possibly also to improve the prognosis. beta-blockade is effective in treating effort-related angina, as are calcium antagonists, which are also effective in treating ...
David Mulcahy, Kim Fox, H. Purcell
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Pharmacotherapy of Unstable Angina
The Journal of Clinical Pharmacology, 1992All patients with unstable angina should be admitted to a coronary or an intensive care unit. There should be an attempt to classify the patient according to the proposed Braunwald nomenclature. If the patient has a secondary cause for unstable angina (e.g., tachyarrhythmia, heart failure, fever, thyrotoxicosis, severe hypertension, hypoxia, unusual ...
L. Houghton+5 more
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