Results 141 to 150 of about 315,851 (243)
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, EarlyView.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Deviation From Genetically Predicted BMI and All‐Cause Mortality: A Cohort Study in the UK Biobank
Obesity, EarlyView.ABSTRACT Objective The relation between genetically predicted BMI (gBMI) and actual BMI may have health effects. This study examines the relationship between deviations from gBMI and all‐cause mortality in 208,146 UK Biobank participants. Methods We derived gBMI from polygenic risk scores, with deviations calculated as the difference between observed ...
Nuno R. Zilhao +4 more
wiley +1 more source
Association of Obesity Severity With Cardiometabolic and Renal Disease Burden in the United States
Obesity, EarlyView.ABSTRACT Objective This study examined the association between obesity severity and cardiometabolic and renal disease, using BMI as a surrogate for obesity severity. Methods This is a cross‐sectional study using data from the United States Behavioral Risk Factor Surveillance System (BRFSS), 2011–2023.
Florina Corpodean +7 more
wiley +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Patients with large vestibular schwannomas (VS) are at higher risk for adverse outcomes following microsurgical resection. This study aims to identify clinical and radiographic factors that may be predictive of adverse outcomes. Study Design Retrospective chart review. Setting Academic tertiary care center.
Jason L. Steele +8 more
wiley +1 more source
Proteomic Biomarkers Are Linked to QTc Interval in Patients With Chronic Heart Failure
PROTEOMICS – Clinical Applications, EarlyView.ABSTRACT Objective This study investigates the link between circulating proteins and rate‐corrected QT (QTc) interval in patients with heart failure with reduced ejection fraction (HFrEF) and their association with cardiovascular outcomes. Methods and Results We analyzed 197 HFrEF patients from the prospective Serial Biomarker Measurements and New ...
Mylène Barry‐Loncq de Jong +14 more
wiley +1 more source
Seasonality of thrombogenic disorders in coronary atherosclerosis recrudescence
Russian Open Medical Journal, 2012 Seasonality of thrombogenic disorders in coronary atherosclerosis recrudescence has been studied using a comparison of blood clotting peculiarities in patients with stable (n=167) and unstable angina (n=210) in different season periods.
Liliana K. Tokaeva +2 more
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Target Trial Emulation of Beta‐Blockers After Diagnosis of Colorectal Polyps—Beneficial in Women
United European Gastroenterology Journal, EarlyView.ABSTRACT Background and Aims Beta‐blockers are successfully used to treat hemangioma and may decrease the proliferation of cancer cells. We hypothesized that individuals with colorectal polyps may also benefit from beta‐blocker initiation. Methods Individuals diagnosed with their first colorectal polyp 2006–2016 in the nationwide Swedish ESPRESSO ...
Louise Emilsson +3 more
wiley +1 more source
Device-Based Therapies for Refractory Angina. [PDF]
J Clin MedCaffè A, Montone RA.
europepmc +1 more source
The Journal of Dermatology, EarlyView.ABSTRACT Patients with psoriasis experience significantly higher cardiovascular morbidity compared to the general population. Although certain psoriasis treatments may confer cardioprotective effects, current clinical guidelines addressing treatment continuation following major adverse cardiovascular events (MACE) are lacking. Therefore, we conducted a
Hyun Keun Ahn, Sohee Oh, Hyun‐Sun Yoon
wiley +1 more source