Results 221 to 230 of about 317,688 (293)

Combination Versus Monotherapy in Acute Anti‐LGI1 Encephalitis: A Real‐World Dose Optimization Analysis

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Combined IVIg and 500 mg/day IVMP achieve superior efficacy over monotherapies in anti‐LGI1 encephalitis, with optimal safety. Higher‐dose IVMP (1000 mg) accelerates response but increases adverse events, particularly in diabetic patients. Cognitive deficits persist post‐treatment, necessitating long‐term management.
Yao Tan   +6 more
wiley   +1 more source

Non-invasive Coronary Functional Tests in Patients with Angina and Non-obstructive Coronary Artery Disease. [PDF]

open access: yesEur Cardiol
Cambise N   +14 more
europepmc   +1 more source

Inhaled 5‐HT1B/1D Receptor Antagonist Attenuates Sumatriptan‐Induced Sensitization of Capsaicin‐Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan‐Associated Adverse Chest Symptoms

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Our previous study suggests that sumatriptan‐induced chest discomfort is associated with hypersensitivity of CSLV afferents via 5‐HT1B/1D receptors on nerve endings. The present study demonstrates that inhaled 5‐HT1B/1D receptor antagonism suppresses this hypersensitivity without compromising antimigraine efficacy, supporting local pulmonary antagonism
Nai‐Ju Chan   +3 more
wiley   +1 more source

Hexahydroquinoline Featuring Amide Functionality: A Promising Scaffold With Calcium Channel Blocking Activity

open access: yesDrug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT Hexahydroquinoline (HHQ) is a widely recognized scaffold that has garnered considerable attention owing to its diverse pharmacological properties. The structure of HHQ includes a 1,4‐dihydropyridine (DHP) ring, which serves as the pharmacophore for the predominant class of drugs known as calcium channel blockers.
Ebru Koçak Aslan   +13 more
wiley   +1 more source

Association between triglyceride-glucose index and OCT-defined high-risk coronary plaques in stable angina. [PDF]

open access: yesBMC Cardiovasc Disord
Ma C   +8 more
europepmc   +1 more source

A Case of Perforated Peritonitis Caused by the Migration of a Single‐Puncture Gastric Wall Fixation Device Following Percutaneous Endoscopic Gastrostomy

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract We report an uncommon case of perforated peritonitis resulting from the migration of a single‐puncture gastric wall fixation device following percutaneous endoscopic gastrostomy. An 83‐year‐old male developed acute peritonitis 6 days post‐procedure, requiring emergency surgery.
Yuu Kodama   +8 more
wiley   +1 more source

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