Results 81 to 90 of about 161,099 (267)

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay   +3 more
wiley   +1 more source

Patients With Nonobstructive Coronary Artery Disease and Chest Pain: Impact of Obesity and Depressive Symptoms

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Chest pain (CP) in patients with nonobstructive coronary artery disease is a therapeutic challenge affecting morbidity and mortality. We aimed to identify clinical factors associated with CP in this population, hypothesizing that obesity and ...
Nishant Vatsa   +14 more
doaj   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

open access: yesObesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter   +14 more
wiley   +1 more source

High‐intensity interval training vs. moderate‐intensity continuous training in COVID‐19 survivors (COVIDEX): A randomized clinical trial on feasibility and short‐term efficacy

open access: yesPM&R, EarlyView.
Abstract Background High‐intensity interval training (HIIT) and moderate‐intensity continuous training (MICT) have been widely studied in individuals with chronic conditions. However, no studies have compared these two exercise modalities in COVID‐19 survivors. Objective To compare the feasibility, safety, adherence, and short‐term efficacy of HIIT and
Vinicius Afonso Gomes   +11 more
wiley   +1 more source

ANGINA PECTORIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1900
n ...
openaire   +2 more sources

Long‐Term Cardiovascular Impact of Postpartum Treatment After Hypertensive Disorders of Pregnancy: Population‐Based Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess whether early antihypertensive treatment after Hypertensive Disorders of Pregnancy (HDP) influences subsequent development of cardiovascular complications. Design and Setting Population‐based nationwide cohort of health data set in France.
Emmanuel Simon   +5 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra   +3 more
wiley   +1 more source

ANGINA PECTORIS. [PDF]

open access: yesThe Lancet, 1903
n ...
openaire   +2 more sources

Association Between Vasomotor Symptoms of Menopause and Retirement: A Prospective Longitudinal Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess the association between vasomotor symptoms of menopause and retirement in Australian women. Design Population‐based cohort study. Setting Secondary analysis of six surveys collected between 1996 and 2010. Population A total of 6928 Australian women, born between 1946 and 1951. Methods Data were obtained from participants in
Biresaw Wassihun Alemu   +2 more
wiley   +1 more source

The Prevalence and Epidemiological Features of Ischaemic Heart Disease in Sri Lanka

open access: yesGlobal Heart
Background: There is limited evidence on the prevalence of ischaemic heart disease (IHD) and its association with risk factors and socioeconomic status (SES) in low- and middle-income countries (LMICs).
Nilmini Wijemunige   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy